3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features

NARecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

October 19, 2022

Primary Completion Date

October 9, 2025

Study Completion Date

October 9, 2026

Conditions
Meningioma
Interventions
DIAGNOSTIC_TEST

Magnetic Resonance Elastography

Participants will undergo preoperative 3D MRE to quantify tumor stiffness and generate adhesion maps. MRE is performed as an adjunct to standard brain MRI, using 60 Hz vibration frequency and specialized elastogram processing software. The resulting stiffness and adhesion data are made available to the neurosurgical team for surgical planning.

PROCEDURE

Intraoperative Assessment and Recording

During surgical resection, the neurosurgical team will systematically assess and record tumor stiffness, adhesion to surrounding structures, vascularity, resection time, and technical difficulty using a standardized intraoperative scale. These intraoperative findings will be compared to preoperative MRE parameters to evaluate the diagnostic and predictive value of MRE.

Trial Locations (1)

110000

RECRUITING

Shengjing Hospital, Shenyang

All Listed Sponsors
lead

Shengjing Hospital

OTHER