Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

January 28, 2026

Study Completion Date

February 28, 2026

Conditions
Hernia, VentralPain Management
Interventions
PROCEDURE

Quadratus Lumborum (QL) Block

"The intervention arm will receive bilateral quadratus lumborum blocks in the preoperative holding area prior to surgery. The syringe will contain a total of 60 mL of 0.25% Ropivacaine with 4 mg of Decadron. The anesthesiology pain team provider will administer 30 mL on the left side and 30 mL on the right side of the abdominal wall. The patient will receive one injection site per flank. During the procedure, the patient is placed in the left and then right lateral decubitus position and the ultrasound probe is placed above the iliac crest at the mid axillary line. The pain team provider will move the probe posteriorly to identify the shamrock sign. Under ultrasound guidance, a needle is inserted in an in- plane approach through the quadratus lumborum (QL) muscle until reaching the middle of the thoracolumbar fascia layer between QL and psoas muscle. After negative aspiration for blood, injection will allow the spread of local anesthetic between the QL and psoas muscle on each side."

PROCEDURE

Placebo

"The placebo control group will receive the same quadratus lumborum (QL) block procedure as the intervention group, with the only difference being the injection of 60 mL of saline instead of local anesthetic. The anesthesiology team will administer 30 mL on each side of the abdominal wall, with one injection site per flank. The patient will be positioned in the left and right lateral decubitus positions, and the ultrasound probe will be placed above the iliac crest at the mid-axillary line to identify the shamrock sign. The needle will be inserted through the QL muscle to the thoracolumbar fascia layer, between the QL and psoas muscle. After negative aspiration for blood, saline will be injected, allowing spread between the QL and psoas muscle on each side."

Trial Locations (1)

37920

The University of Tennessee Medical Center, Knoxville

All Listed Sponsors
lead

University of Tennessee Graduate School of Medicine

OTHER

NCT06953635 - Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair | Biotech Hunter | Biotech Hunter