NCT06951906 - Imaging Biomarkers of FOG Response to DBS | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 11, 2024

Primary Completion Date

November 30, 2029

Study Completion Date

January 31, 2030

Conditions

Freezing of Gait Symptoms in Parkinson's DiseaseDeep Brain Stimulation

Interventions

DIAGNOSTIC_TEST

fMRI

Baseline imaging will utilize advanced diffusion MRI metrics to determine which brain areas are structurally connected to the stimulation target and their structural integrity. Post-operative assessments will include behavioral measures of FOG response and imaging measures of neural response to stimulation. Pre- and post-operative data will be used to evaluate the association between structural integrity, connectivity and behavioral response.

Trial Locations (1)

29425

RECRUITING

Medical University of South Carolina, Charleston

All Listed Sponsors

collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Medical University of South Carolina

OTHER