128
Participants
Start Date
May 15, 2025
Primary Completion Date
February 28, 2027
Study Completion Date
March 31, 2029
radiotherapy
Radiotherapy: Administer three-dimensional conformal/intensity-modulated/TOMO radiotherapy with a conventional fractionation schedule of 36-41.4 Gy in 20-23 fractions (1.8 Gy per fraction).
CAPOX
4 cycles, Oxaliplatin 130 mg/m², Capecitabine 825 mg/m²
Capecitabine
Administer Capecitabine at a dose of 825 mg/m², twice daily, orally on radiotherapy days
Iparomlimab and Tuvonralimab Injection
IV, 5 mg/kg every 3 weeks
RECRUITING
the Fourth Hospital of Hebei Medical University, Shijiazhuang
Hebei Medical University Fourth Hospital
OTHER