NCT06949098View on ClinicalTrials.gov

Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 15, 2025

Primary Completion Date

March 31, 2032

Study Completion Date

May 31, 2032

Conditions
Rectal Cancer Stage I
Interventions
PROCEDURE

Local Tumor Resection

All enrolled patients will first undergo local tumor resection.

RADIATION

Radiotherapy

"Pelvic field irradiation 45Gy in 25 fractions plus Local tumor bed boost 5.4Gy in 3 fractions.~For patients with positive surgical margins after local resection, a radiotherapy boost (pelvic field 45Gy/25 fractions + tumor bed local boost 14.4Gy/8 fractions) can be given."

DRUG

Chemotherapy

Concurrent oral capecitabine 825 mg/m² twice daily with radiotherapy

Trial Locations (1)

Unknown

RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

Hebei Medical University Fourth Hospital

OTHER