RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID

NANot yet recruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
Skin LaxityFacial Aging
Interventions
PROCEDURE

PLLA application to the mandibular angle

The investigator will mark the application area by palpating the inferior and posterior boundaries of the face and the mandibular ramus, approximately 1 cm from these anatomical landmarks. The second PLLA injection point will be marked 1 cm from the inferior bony border of the mandible, anterior to the mandibular ligament. The demarcated area will be anesthetized with a local infiltration of 0.3-0.5 mL of 1% lidocaine with epinephrine, using a 30G needle. PLLA will then be reconstituted in 10 mL of sterile water for injection. Administration will be performed with a 30G needle inserted perpendicularly into the marked area until the supraperiosteal plane of the mandibular angle is reached, delivering a 0.7 mL bolus of the reconstituted product. At the second site-1 cm from the inferior bony border of the mandible, anterior to the mandibular ligament-a 0.2 mL dose of the reconstituted product will be injected.

All Listed Sponsors
collaborator

HEXSEL DERMATOLOGIC CLINICS RESEARCH DEPARTMENT

UNKNOWN

lead

Doris Hexsel

OTHER

NCT06948045 - RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID | Biotech Hunter | Biotech Hunter