Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed

NAEnrolling by invitationINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

April 27, 2026

Study Completion Date

April 27, 2026

Conditions
Laparoscopic Appendectomy
Interventions
PROCEDURE

Rectus Sheath Block

Bilateral rectus sheath blocks using an in-plane ultrasound-guided technique with 0.25% bupivacaine with epinephrine 1:200 000 at 0.8 mL/kg (half of total volume per side) up to a maximum of 20 mL prior to the incision.

DRUG

Local Anesthetic at the Umbilical Port Site

0.25% bupivacaine with epinephrine 1:200 000. Total dose of 0.8 mL/kg (maximum 20 mL) at the umbilical port site.

DRUG

Intravenous Dexamethasone

Intravenous Dexamethasone delivered concurrent to the RSB. Total dose of 150 mcg/kg up to a maximum of 8 mg.

DRUG

Local Anesthetic at the Incision Site

The remaining volume of local anesthetic (0.2 mL/kg) can be infiltrated at each of the incision sites at the discretion of the surgeon up to a maximum of 10 mL.

Trial Locations (1)

V6H 3N1

British Columbia Children's Hospital, Vancouver

All Listed Sponsors
collaborator

BC Children's Hospital Research Institute

OTHER

lead

University of British Columbia

OTHER