Same-day Radioembolization for Large HCC

RecruitingOBSERVATIONAL
Enrollment

138

Participants

Timeline

Start Date

April 25, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2029

Conditions
Hepatocellular Carcinoma (HCC)
Interventions
PROCEDURE

same-day radioembolization

"On the day of the procedure, angiography is performed, followed by cone-beam CT of the hepatic artery. After injecting 99mTc-MAA into the hepatic artery, the patient is transferred to the nuclear medicine department for a lung shunt scan and lung SPECT/CT. The lung shunt fraction is determined using the planar images.~Using diagnostic CT/MRI and 99mTc-MAA images, the treatment dose is calculated with the multi-compartment MIRD method. The acceptable range for tumor absorbed dose is ≥100 Gy, and the lung dose must be ≤15 Gy. The tumor absorbed dose must be at least 100 Gy and should ideally be within the range of 300 to 600 Gy. There is no upper limit for the tumor absorbed dose."

Trial Locations (4)

Unknown

RECRUITING

National Cancer Center, Goyang

NOT_YET_RECRUITING

Samsung Medical Center, Seoul

RECRUITING

Seoul National University Hospital, Seoul

NOT_YET_RECRUITING

Severance hospital, Seoul

All Listed Sponsors
lead

Seoul National University Hospital

OTHER