Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination

NANot yet recruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

February 1, 2026

Primary Completion Date

April 1, 2026

Study Completion Date

May 30, 2026

Conditions
Knee ProsthesisKnee Prosthesis InfectionDisbiosis
Interventions
PROCEDURE

total knee replacement

The Orthopedic Surgeon will remove the damaged cartilage and bone then implant the new metal and plastic knee to restore the alignment and function of your knee. The surgical procedure takes about 1-2 hours on average. While in case of infection, an antibiotic cement is inserted, which will be removed with the subsequent prosthetic implant surgery. Finally, prosthetic components can be more filling, depending on the amount of bone that is previously removed.

All Listed Sponsors
collaborator

Azienda Ospedaliera di Rilievo Nazionale A.Cardarelli

OTHER

lead

Istituto Clinico Humanitas

OTHER

NCT06944288 - Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination | Biotech Hunter | Biotech Hunter