CsA vs MMC for Preventing Pterygium Recurrence

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

September 30, 2024

Study Completion Date

October 15, 2024

Conditions
PterygiumPterygium of the Conjunctiva and Cornea
Interventions
PROCEDURE

Excision of the pterygium

The surgical procedure involved excision of the pterygium, including the fibrovascular head and associated conjunctival tissue, followed by bare sclera closure using an autologous conjunctival graft harvested from the superior bulbar conjunctiva. The graft was secured in place using either fibrin glue or 8-0 absorbable sutures. In Group B, 0.02% mitomycin C (MMC) was applied to the bare sclera for two minutes using a soaked sponge, followed by thorough irrigation with balanced salt solution.

DRUG

Post-operative application of CsA

Patients received topical cyclosporin A (0.05%) twice daily for three months postoperatively.

DRUG

Intra-operative application of MMC

0.02% mitomycin C (MMC) was applied to the bare sclera for two minutes using a soaked sponge, followed by thorough irrigation with balanced salt solution.

Trial Locations (1)

4450113

Ebsar Eye Center, Cairo

All Listed Sponsors
lead

Benha University

OTHER

NCT06944132 - CsA vs MMC for Preventing Pterygium Recurrence | Biotech Hunter | Biotech Hunter