Direct Ischemic Conditioning for Endovascular Recanalization for Anterior Large Vessel Occlusion (DICER-aLVO)

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

January 1, 2026

Study Completion Date

March 31, 2026

Conditions
Ischemic Stroke
Interventions
PROCEDURE

Direct Ischemic Conditioning A

Direct Ischemic Conditioning initiated within 5 minutes post-revascularization using either a balloon guiding catheter or a balloon catheter, positioned at the C1 segment of the ipsilateral internal carotid artery (ICA) to temporarily halt antegrade flow. The protocol comprised 5 cycles of 30-s balloon inflations and 30-s deflations.

PROCEDURE

Direct Ischemic Conditioning B

Direct Ischemic Conditioning initiated within 5 minutes post-revascularization using either a balloon guiding catheter or a balloon catheter, positioned at the C1 segment of the ipsilateral internal carotid artery (ICA) to temporarily halt antegrade flow. The protocol comprised 4 cycles of 60-s balloon inflations and 60-s deflations.

PROCEDURE

Direct Ischemic Conditioning C

Direct Ischemic Conditioning initiated within 5 minutes post-revascularization using either a balloon guiding catheter or a balloon catheter, positioned at the C1 segment of the ipsilateral internal carotid artery (ICA) to temporarily halt antegrade flow. The protocol comprised 3 cycles of 120-s balloon inflations and 120-s deflations.

Trial Locations (1)

110016

RECRUITING

General Hospital of Northern Theater Command, Shengyang

All Listed Sponsors
lead

General Hospital of Shenyang Military Region

OTHER