NCT06939335View on ClinicalTrials.gov

The Application of Positive End-Expiratory Pressure in Out-of-Hospital Cardiac Arrest: The Lazarus-PEEP Trial.

PHASE3RecruitingINTERVENTIONAL
Enrollment

132

Participants

Timeline

Start Date

April 25, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

February 1, 2027

Conditions
Cardiac Arrest (CA)Out-of-hospital Cardiac Arrest (OHCA)Positive End-expiratory Pressure (PEEP)Ventilation During Resuscitation
Interventions
DEVICE

Disposable PEEP Valve set at 5 cm H20.

Ventilation during cardiac arrest with an adult Resuscitation Bag with a pressure relief valve set at 40 cm H20 and a 22 mm disposable PEEP Valve set at 5 cm H20.

DEVICE

Controle

Ventilation during cardiac arrest with an adult Resuscitation Bag with a pressure relief valve set at 40 cm H20 without a disposable PEEP Valve.

Trial Locations (5)

8300

RECRUITING

AZ Zeno, Knokke

B-9300

RECRUITING

AZORG: campus Merestraat, Aalst

RECRUITING

AZORG: Campus Moorselbaan, Aalst

B-9500

RECRUITING

AZORG: campus Geraardsbergen, Geraardsbergen

B-9240

RECRUITING

UZ Ghent, Ghent

All Listed Sponsors
lead

University Hospital, Ghent

OTHER