Wether VNS in Early Stage (3 Months) is Safe and More Beneficial for Post-stroke Motor Rehabilitation

PHASE1RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

December 30, 2026

Conditions
StrokeMotor Rehabilitation
Interventions
DEVICE

Vagus Nerve Stimulation in early stage

Device implantation was done under general anaesthesia. A horizontal neck crease incision was created left of the midline at the level of the cricoid cartilage. After the vagus nerve was identified, the stimulation lead was wrapped around the vagus nerve. The lead was then tunnelled subcutaneously to the pulse generator device which was contained in a subcutaneous pocket in the pectoral region.

DEVICE

Vagus Nerve Stimulation in late stage

Device implantation was done under general anaesthesia. A horizontal neck crease incision was created left of the midline at the level of the cricoid cartilage. After the vagus nerve was identified, the stimulation lead was wrapped around the vagus nerve. The lead was then tunnelled subcutaneously to the pulse generator device which was contained in a subcutaneous pocket in the pectoral region

Trial Locations (1)

250100

RECRUITING

Qilu Hospital of Shandong University, Jinan

All Listed Sponsors
lead

Qilu Hospital of Shandong University

OTHER