Comparison of 40% Glucose Solution and Autologous Blood Patch Pleurodesis for Postoperative Air Leak After Lung Resections

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

December 22, 2023

Primary Completion Date

December 1, 2026

Study Completion Date

May 31, 2027

Conditions
Prolonged Air LeakPersistent Air Leak
Interventions
PROCEDURE

Autologous blood patch pleurodesis

The intervention in this study is distinguished by the fact that patients are randomized, the dose of both glucose and ABPP is 120 ml, the patient remains in a supine position for 2 hours after administration, the procedure can be repeated at 48-hour intervals, a maximum of 3 times.

PROCEDURE

40% glucose solution pleurodesis

"After obtaining informed consent, the patient will lie supine in their room. 30 minutes before the procedure, the patient's capillary blood glucose level will be measured. The patient does not have to fast before the procedure. The nurse will be asked to collect 120 ml of peripheral venous blood from the patient. Then the doctor, assisted by the nurse, will first administer 20 ml of 1% Lignocaine through the pleural drain, and then after about 5-10 minutes, the patient's previously collected venous blood. At the moment of blood administration, the drainage system will be disconnected. Then, the drain will be injected with 20 ml of air to avoid clogging the drain. The patient will remain supine for two hours post-procedure, maintaining fasting status. After 30 minutes from the administration of the patient's own blood, the capillary blood glucose level will be measured again. After two hours, the patient, with nursing assistance, may resume normal activities."

Trial Locations (1)

60-569

RECRUITING

Wielkopolskie Centrum Pulmonologii i Torakochirurgii, Poznan

All Listed Sponsors
collaborator

Poznan University of Medical Sciences

OTHER

lead

Wielkopolskie Centrum Pulmonologii i Torakochirurgii

OTHER