Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

April 30, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Diabetes Mellitus Type 2
Interventions
DEVICE

Inspiratory Muscle Strength Training (IMST)

A novel form of physical training that uses the diaphragm and accessory respiratory muscles to repeatedly inhale against resistance using a handheld device, generating large negative intrathoracic pressures. The device can be set to different levels of resistance, meaning the intervention and sham groups will undergo the same training, but at 75% and 15% of their maximal inspiratory pressure respectively.

DEVICE

Sham Training

The same training regiment but at much lower resistance, offering little to strength training impact.

Trial Locations (2)

98102

RECRUITING

Seattle Children's Hospital, Seattle

98109

NOT_YET_RECRUITING

University of Washington Medicine Diabetes Institute, Seattle

All Listed Sponsors
collaborator

University of Washington

OTHER

lead

Seattle Children's Hospital

OTHER