Clinical Study on Deep Cervical Lymphatic Trunk Decompression Combined With Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease Treatment

NAEnrolling by invitationINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

January 8, 2025

Primary Completion Date

July 31, 2025

Study Completion Date

October 31, 2025

Conditions
Alzheimer's Disease
Interventions
PROCEDURE

Bilateral Cervical Deep Lymphatic Trunk Decompression Combined with Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease

This intervention involves a surgical approach that combines bilateral cervical deep lymphatic trunk decompression with mid-cervical deep lymph node-external jugular vein anastomosis (LVA) to enhance lymphatic drainage in Alzheimer's Disease (AD) patients. The aim is to reduce the accumulation of neurotoxic substances in the brain, potentially improving cognitive function by facilitating waste clearance via the lymphatic system. The procedure is intended to restore normal lymphatic flow, potentially slowing disease progression in AD patients who have moderate to severe cognitive impairment.

Trial Locations (1)

Unknown

General Hospital of Tianjin Medical University, 154 Anshan Road, Heping District, Tianjin, China, Tianjin

All Listed Sponsors
lead

Oriental Neurosurgery Evidence-Based-Study Team

OTHER