45
Participants
Start Date
January 8, 2025
Primary Completion Date
July 31, 2025
Study Completion Date
October 31, 2025
Bilateral Cervical Deep Lymphatic Trunk Decompression Combined with Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease
This intervention involves a surgical approach that combines bilateral cervical deep lymphatic trunk decompression with mid-cervical deep lymph node-external jugular vein anastomosis (LVA) to enhance lymphatic drainage in Alzheimer's Disease (AD) patients. The aim is to reduce the accumulation of neurotoxic substances in the brain, potentially improving cognitive function by facilitating waste clearance via the lymphatic system. The procedure is intended to restore normal lymphatic flow, potentially slowing disease progression in AD patients who have moderate to severe cognitive impairment.
General Hospital of Tianjin Medical University, 154 Anshan Road, Heping District, Tianjin, China, Tianjin
Oriental Neurosurgery Evidence-Based-Study Team
OTHER