A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

PHASE3RecruitingINTERVENTIONAL
Enrollment

264

Participants

Timeline

Start Date

June 13, 2025

Primary Completion Date

June 20, 2026

Study Completion Date

January 10, 2027

Conditions
HyperphosphatemiaChronic Kidney Disease, Receiving DialysisESRD (End-Stage Renal Disease)Dialysis
Interventions
DRUG

AP301

Three times a day, administered orally with three meals at a daily dose level from 2.7g to 9.0g

DRUG

AP301 Low Dose

Three times a day, administered orally with three meals at a daily dose level from 0.075g to 0.25g

Trial Locations (31)

14215

RECRUITING

US Renal Care - West Cheektowaga, Cheektowaga

30720

RECRUITING

Nephrology & Hypertension Specialists, Dalton

33912

RECRUITING

US Renal Care - Fort Myers South, Fort Myers

43613

RECRUITING

US Renal Care - Alexis, Toledo

76110

NOT_YET_RECRUITING

US Renal Care - South San Antonio, Fort Worth

78211

RECRUITING

US Renal Care - South San Antonio, San Antonio

78251

NOT_YET_RECRUITING

US Renal Care - Hill Country, San Antonio

80124

RECRUITING

Rocky Mountain Kidney Care - Lone Tree, Lone Tree

100035

NOT_YET_RECRUITING

Peking University First Hospital, Beijing

102218

NOT_YET_RECRUITING

Beijing Tsinghua Chang Gung Hospital, Beijing

NOT_YET_RECRUITING

Peking University International Hospital, Beijing

200000

NOT_YET_RECRUITING

Shanghai Jiao Tong University School of Medicine (SJTUSM)-Renji Hospital, Shanghai

200032

NOT_YET_RECRUITING

Fudan University-Zhongshan Hospital, Shanghai

200040

NOT_YET_RECRUITING

Fudan University-Huashan Hospital, Shanghai

200336

NOT_YET_RECRUITING

Shanghai Tongren Hospital, Shanghai

210009

NOT_YET_RECRUITING

Southeast University-Zhongda Hospital, Nanjing

210029

NOT_YET_RECRUITING

Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University), Nanjing

214023

NOT_YET_RECRUITING

Nanjing Medical University-Wuxi People's Hospital (Wuxi No.1 People's Hospital), Wuxi

225002

NOT_YET_RECRUITING

Subei People's Hospital, Yangzhou

226001

NOT_YET_RECRUITING

Nantong University-Affiliated Hospital, Nantong

264099

NOT_YET_RECRUITING

Yantai Yuhuangding Hospital, Yantai

266000

NOT_YET_RECRUITING

Qingdao University-The Affiliated Hospital, Qingdao

330006

NOT_YET_RECRUITING

Jiangxi Provincial People's Hospital, Nanchang

361003

NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

410013

NOT_YET_RECRUITING

Central South University-The Third Xiangya Hospital, Changsha

430022

NOT_YET_RECRUITING

Huazhong University of Science and Technology-Tongji Medical College - Wuhan Union Hospital, Wuhan

430060

NOT_YET_RECRUITING

Wuhan University People's Hospital, Wuhan

450003

NOT_YET_RECRUITING

Henan Provincial People's Hospital, Zhengzhou

NOT_YET_RECRUITING

Zhengzhou University-First Affiliated Hospital, Zhengzhou

610072

NOT_YET_RECRUITING

Sichuan Provincial People's Hospital, Chengdu

06477

RECRUITING

PACT Kidney Care - Orange, Orange

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Fortrea

INDUSTRY

lead

Alebund Pharmaceuticals

INDUSTRY