PLADO for Conservative Management of CKD

NARecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

May 28, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Chronic Kidney Disease(CKD)Metabolic Acidosis
Interventions
OTHER

PLADO

Low protein plant-dominant diet (PLADO) of 0.6-0.8 g/kg/day of proteins with at least 50% plant-based sources, sodium of \<4 g/day and \<3 g/day in case of edema or hypertension, fibers of 25-30 g/day, and calories of 30-35 Kcal/kg/day provided in the form of individualized meal plans administered by a licensed/registered dietitian. The nutrition education intervention will be provided via a primary face-to-face education/counseling session of 45-60 minutes, followed by a monthly face-to-face follow-up session of 30-45 minutes for 6 months, and a face-to-face follow-up session of 30-45 minutes after 3 months. At each visit, participants will be screened according to the Transtheoretical behavior change model (TTM) using a TTM-based algorithm to determine their stage/readiness to adhere to PLADO and will receive stage-based education and counseling accordingly. Stage-based education will be divided into 1) Pre-contemplation and contemplation; 2) Preparation; and 3) Action and Maintenance

OTHER

Standard-of-care diet

Current standard-of-care diet composed of dietary protein, fluid, sodium potassium, and phosphorus restrictions provided via monthly face-to-face sessions of 30-45 minutes over a period of 6 months, and a follow-up session after 3 months provided by the same licensed/registered dietitian. Patients will be recruited to the control arm in the same period to avoid seasonal differences.

Trial Locations (1)

Unknown

RECRUITING

Lebanese American University Medical Center- Rizk Hospital, Beirut

All Listed Sponsors
collaborator

Zayed University

OTHER

collaborator

Maastricht University

OTHER

lead

Lebanese American University

OTHER