Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors

NARecruitingINTERVENTIONAL
Enrollment

112

Participants

Timeline

Start Date

March 13, 2025

Primary Completion Date

October 13, 2025

Study Completion Date

October 13, 2025

Conditions
Shock
Interventions
DRUG

Weaning critically ill patients from norepinephrine using midodrine as an adjuvant to norepinephrine

• Patients in group I will receive midodrine (10 mg orally every 8 hours) in addition to administered concurrently with ongoing intravenous norepinephrine after being on norepinephrine for more than 24 hrs.

DRUG

Weaning critically ill patients from norepinephrine without use of midodrine as an adjuvant

Patients in group II with ongoing intravenous norepinephrine only

Trial Locations (1)

Unknown

RECRUITING

Sohag University Hospital, Sohag

All Listed Sponsors
lead

Sohag University

OTHER