450
Participants
Start Date
July 18, 2025
Primary Completion Date
June 13, 2028
Study Completion Date
June 13, 2028
KarXT
Specified dose on specified days
Lithium
Therapeutic dose
Valproate
Therapeutic dose
Lamotrigine
Therapeutic dose
NOT_YET_RECRUITING
Local Institution - 0109, Győr
NOT_YET_RECRUITING
Local Institution - 0110, Budapest
NOT_YET_RECRUITING
Local Institution - 0094, Bucharest
NOT_YET_RECRUITING
Local Institution - 0108, Budapest
NOT_YET_RECRUITING
Local Institution - 0107, Novi Iskar
RECRUITING
Ramsay Clinic Northside, St Leonards
NOT_YET_RECRUITING
Local Institution - 0114, Vratsa
RECRUITING
Ramsay Clinic New Farm, Brisbane
NOT_YET_RECRUITING
Local Institution - 0127, Córdoba
NOT_YET_RECRUITING
Local Institution - 0126, Mendoza
NOT_YET_RECRUITING
Local Institution - 0081, Pleven
NOT_YET_RECRUITING
Local Institution - 0082, Burgas
NOT_YET_RECRUITING
Local Institution - 0113, Sliven
WITHDRAWN
Local Institution - 0018, Zagreb
NOT_YET_RECRUITING
Local Institution - 0017, Zagreb
NOT_YET_RECRUITING
Local Institution - 0019, Zagreb
NOT_YET_RECRUITING
Local Institution - 0103, Zagreb
NOT_YET_RECRUITING
Local Institution - 0129, Zagreb
RECRUITING
Richmond Behavioral Associates, Staten Island
NOT_YET_RECRUITING
Local Institution - 0069, Genova
NOT_YET_RECRUITING
Local Institution - 0066, Milan
NOT_YET_RECRUITING
Local Institution - 0152, Smila
NOT_YET_RECRUITING
Local Institution - 0049, Gaithersburg
NOT_YET_RECRUITING
Local Institution - 0148, Vinnytsia
NOT_YET_RECRUITING
Local Institution - 0151, Kropyvnytskyi
NOT_YET_RECRUITING
Local Institution - 0124, Charlotte
RECRUITING
CenExel iResearch, LLC, Decatur
RECRUITING
Synexus Clinical Research US, Inc., Atlanta
RECRUITING
Atlanta Center for Medical Research, Atlanta
NOT_YET_RECRUITING
Local Institution - 0146, Skarzhyntsi
NOT_YET_RECRUITING
Local Institution - 0024, Savannah
NOT_YET_RECRUITING
Local Institution - 0133, Hallandale
NOT_YET_RECRUITING
Local Institution - 0026, Hialeah Gardens
RECRUITING
Innovative Clinical Research, Inc., Miami Lakes
RECRUITING
Behavioral Clinical Research, Hollywood
NOT_YET_RECRUITING
Local Institution - 0053, Hollywood
NOT_YET_RECRUITING
Local Institution - 0030, Miami
RECRUITING
Advanced Research Institute of Miami, Miami
RECRUITING
South Florida Research Phase I-IV, Miami Springs
NOT_YET_RECRUITING
Local Institution - 0045, St. Petersburg
RECRUITING
Health Synergy Clinical Research, Stuart
NOT_YET_RECRUITING
Local Institution - 0141, Poltava
NOT_YET_RECRUITING
Local Institution - 0029, Flowood
RECRUITING
Neuro-Behavioral Clinical Research, North Canton
NOT_YET_RECRUITING
Local Institution - 0055, Cincinnati
RECRUITING
Osi Bilbao-Basurto, Bilbao
NOT_YET_RECRUITING
Local Institution - 0149, Dnipro
NOT_YET_RECRUITING
Local Institution - 0065, Siena
NOT_YET_RECRUITING
Local Institution - 0083, Pisa
NOT_YET_RECRUITING
Local Institution - 0070, Ancona
NOT_YET_RECRUITING
Local Institution - 0031, Chicago
RECRUITING
Pillar Clinical Research -Chicago, Chicago
NOT_YET_RECRUITING
Local Institution - 0042, St Louis
NOT_YET_RECRUITING
Local Institution - 0144, Odesa
NOT_YET_RECRUITING
Local Institution - 0145, Oleksandrivka
RECRUITING
Pillar Clinical Research- Little Rock, Little Rock
NOT_YET_RECRUITING
Local Institution - 0038, Little Rock
RECRUITING
Pillar Clinical Research - Richardson, Bentonville
NOT_YET_RECRUITING
Local Institution - 0057, Rogers
WITHDRAWN
Local Institution - 0036, Irving
RECRUITING
Pillar Clinical Research - Richardson, Richardson
RECRUITING
InSite Clinical Research, DeSoto
NOT_YET_RECRUITING
Local Institution - 0142, Ivano-Frankivsk
NOT_YET_RECRUITING
Local Institution - 0046, Houston
NOT_YET_RECRUITING
Local Institution - 0134, Austin
NOT_YET_RECRUITING
Local Institution - 0147, Lviv
NOT_YET_RECRUITING
Local Institution - 0120, Glendale
NOT_YET_RECRUITING
Local Institution - 0121, North Las Vegas
WITHDRAWN
Local Institution - 0122, North Las Vegas
RECRUITING
Proscience Research Group, Culver City
NOT_YET_RECRUITING
Local Institution - 0123, Torrance
NOT_YET_RECRUITING
Local Institution - 0044, Cerritos
RECRUITING
Clinical Innovations, Inc. dba CITrials, Bellflower
NOT_YET_RECRUITING
Local Institution - 0135, Chino
NOT_YET_RECRUITING
Local Institution - 0056, Montclair
RECRUITING
Clinical Innovations, Inc. dba CITrials, Riverside
NOT_YET_RECRUITING
Local Institution - 0027, Anaheim
RECRUITING
NRC Research Institute, Orange
NOT_YET_RECRUITING
Local Institution - 0077, Ludhiana
NOT_YET_RECRUITING
Local Institution - 0111, Vadodara
NOT_YET_RECRUITING
Local Institution - 0078, Hyderabad
NOT_YET_RECRUITING
Local Institution - 0080, Hyderabad
NOT_YET_RECRUITING
Local Institution - 0100, Sanpetru /Brasov
NOT_YET_RECRUITING
Local Institution - 0132, Belagavi
NOT_YET_RECRUITING
Local Institution - 0079, Kozhikode
NOT_YET_RECRUITING
Local Institution - 0076, Kolkata
NOT_YET_RECRUITING
Local Institution - 0097, Iași
NOT_YET_RECRUITING
Local Institution - 0068, Hod HaSharon
NOT_YET_RECRUITING
Local Institution - 0008, Kōnan
NOT_YET_RECRUITING
Local Institution - 0084, Petah Tikva
RECRUITING
Sheba Medical Center, Ramat Gan
NOT_YET_RECRUITING
Local Institution - 0075, Ness Ziona
RECRUITING
Be'er Sheva Mental Health Center, Beersheba
NOT_YET_RECRUITING
Local Institution - 0074, Jerusalem
NOT_YET_RECRUITING
Local Institution - 0085, Garden Grove
NOT_YET_RECRUITING
Local Institution - 0131, New Haven
WITHDRAWN
Local Institution - 0058, Marlton
NOT_YET_RECRUITING
Local Institution - 0130, Marlton
NOT_YET_RECRUITING
Local Institution - 0128, ABB
RECRUITING
Okehazama Hospital, Toyoake
RECRUITING
National Kohnodai Medical Center., Ichikawa
WITHDRAWN
Local Institution - 0063, Kitakyushu
RECRUITING
Obihiro Kosei Hospital, Obihiro
RECRUITING
Goryokai Medical Corporation - Goryokai Hospital, Sapporo
NOT_YET_RECRUITING
Local Institution - 0007, Sakai-shi
RECRUITING
Rainbow and Sea Hospital, Karatsu-shi
WITHDRAWN
Local Institution - 0016, Iruma
RECRUITING
Saitama Konan Hospital, Kumagaya
RECRUITING
National Center of Neurology and Psychiatry, Kodaira
RECRUITING
Narimasu Kosei Hospital, tabashi City
RECRUITING
Kuramitsu Hospital, Fukuoka
NOT_YET_RECRUITING
Local Institution - 0004, Miyazaki
RECRUITING
Osaka Metropolitan University Hospital, Osaka
NOT_YET_RECRUITING
Local Institution - 0013, Osaka
RECRUITING
Showa Medical University Karasuyama Hospital, Tokyo
NOT_YET_RECRUITING
Local Institution - 0002, Wakayama
NOT_YET_RECRUITING
Local Institution - 0014, Yamagata
NOT_YET_RECRUITING
Local Institution - 0086, Auckland
NOT_YET_RECRUITING
Local Institution - 0088, Poznan
NOT_YET_RECRUITING
Local Institution - 0092, Warsaw
NOT_YET_RECRUITING
Local Institution - 0090, Bialystok
NOT_YET_RECRUITING
Local Institution - 0093, Gdansk
NOT_YET_RECRUITING
Local Institution - 0089, Rybnik
NOT_YET_RECRUITING
Local Institution - 0091, Tuszyn
NOT_YET_RECRUITING
Local Institution - 0095, Bucharest
NOT_YET_RECRUITING
Local Institution - 0099, Bucharest
NOT_YET_RECRUITING
Local Institution - 0101, Bucharest
RECRUITING
Prof. Dr. Alexandru Obregia Psychiatry Hospital, Bucharest
RECRUITING
Prof. Dr. Alexandru Obregia Psychiatry Hospital, Bucharest
RECRUITING
Prof. Dr. Alexandru Obregia Psychiatry Hospital, Bucharest
NOT_YET_RECRUITING
Local Institution - 0104, Bucharest
NOT_YET_RECRUITING
Local Institution - 0118, Košice
NOT_YET_RECRUITING
Local Institution - 0119, Košice
NOT_YET_RECRUITING
Local Institution - 0117, Vranov nad Topľou
NOT_YET_RECRUITING
Local Institution - 0115, Barcelona
RECRUITING
Hospital Clínic de Barcelona, Barcelona
RECRUITING
Nacka Local Hospital, Nacka
WITHDRAWN
Local Institution - 0112, Uppsala
WITHDRAWN
Local Institution - 0116, Gothenburg
NOT_YET_RECRUITING
Local Institution - 0143, Hlevakha
NOT_YET_RECRUITING
Local Institution - 0150, Kyiv
Lead Sponsor
Bristol-Myers Squibb
INDUSTRY