Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries

NANot yet recruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Laparoscopic SurgeryPneumoperitoneumPositive End Expiratory Pressure (PEEP)
Interventions
OTHER

Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries

Protective lung ventilation methods with positive end-expiratory pressure help in prevention of atelectasis and improvement of intraoperative ventilator parameters e.g low driving pressure and improved dynamic compliance resulting in better oxygenation of lungs ere will be three groups in this study. Individualized positive end-expiratory pressure with recruitment maneuver and fixed positive end-expiratory pressure will be interventional groups. They will be compared with conventional ventilation group in which no additional positive end-expiratory pressure will be applied. The effects on respiratory parameters and oxygenation of patients will be compared for each group. This study will determine which method of positive end-expiratory pressure is superior and how it differs from conventional ventilation for prevention of atelectasis induced by pneumoperitonium and improvement of respiratory mechanical parameters and oxygenation in Mechanical ventilation during laparoscopic surgeries.

Trial Locations (1)

63100

Combined Military Hospital Bahawalpur, Bahawalpur

All Listed Sponsors
lead

Noor-Ul-Ain

OTHER

NCT06929078 - Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries | Biotech Hunter | Biotech Hunter