NCT06927076View on ClinicalTrials.gov

Antidepressant Response of DMT Masked With Propofol

NARecruitingINTERVENTIONAL
Enrollment

112

Participants

Timeline

Start Date

August 5, 2025

Primary Completion Date

March 31, 2029

Study Completion Date

March 31, 2029

Conditions
Major Depressive DisorderPsychedelic Experiences
Interventions
DRUG

N,N-Dimethyltryptamine

administration of a 2mg/min DMT perfusion over 20 min

DRUG

Placebo

administration of a placebo perfusion over 20 min

PROCEDURE

Propofol

30 min propofol sedation

PROCEDURE

no sedation

no sedation

Trial Locations (1)

4031

RECRUITING

University Hospital Basel, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER

NCT06927076 - Antidepressant Response of DMT Masked With Propofol | Biotech Hunter | Biotech Hunter