A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

416

Participants

Timeline

Start Date

July 18, 2025

Primary Completion Date

January 8, 2027

Study Completion Date

January 8, 2027

Conditions
Chronic Kidney Disease
Interventions
DRUG

Vicadrostat

Vicadrostat

DRUG

Empagliflozin

Empagliflozin

DRUG

Placebo matching vicadrostat

Placebo matching vicadrostat

Trial Locations (162)

807

NOT_YET_RECRUITING

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

850

NOT_YET_RECRUITING

Philippine Heart Center, Quezon City

1012

NOT_YET_RECRUITING

IDIM - Instituto de Diagnostico e Investigaciones Metabolicas, Buenos Aires

1070

NOT_YET_RECRUITING

ULB Hopital Erasme, Brussels

1200

NOT_YET_RECRUITING

Cliniques Universitaires Saint-Luc, Brussels

1407

NOT_YET_RECRUITING

CEMEDIC - Centro de Especialidades Medicas, Villa Luro

1810

NOT_YET_RECRUITING

Institute for Studies on Diabetes Foundation Inc., Marikina City

2145

NOT_YET_RECRUITING

Westmead Hospital, Westmead

2305

NOT_YET_RECRUITING

John Hunter Hospital, New Lambton Heights

2306

NOT_YET_RECRUITING

Senor Santo Nino Hospital, Camiling

3000

NOT_YET_RECRUITING

UZ Leuven, Leuven

3084

NOT_YET_RECRUITING

Austin Health, Heidelberg

3240

NOT_YET_RECRUITING

Waikato Hospital, Hamilton

5036

RECRUITING

Momentum Clinical Research - Kapiti Coast, Kapiti

6000

NOT_YET_RECRUITING

Royal Perth Hospital, Perth

NOT_YET_RECRUITING

Norzel Medical and Diagnostic Clinic, Cebu City

6041

NOT_YET_RECRUITING

Humani - CHU Charleroi - Chimay, Lodelinsart

9016

NOT_YET_RECRUITING

Dunedin Hospital, Dunedin

10048

RECRUITING

National Taiwan University Hospital, Taipei

10330

NOT_YET_RECRUITING

King Chulalongkorn Memorial Hospital, Bangkok

10400

NOT_YET_RECRUITING

Phramongkutklao Hospital, Bangkok

10700

RECRUITING

Siriraj Hospital, Bangkok

11787

NOT_YET_RECRUITING

Endocrine Associates of Long Island, Smithtown

13620

RECRUITING

Seoul National University Bundang Hospital, Seongnam

15009

RECRUITING

Heritage Valley Medical Group, Beaver

15355

NOT_YET_RECRUITING

Korea University Ansan Hospital, Ansan-si

15895

NOT_YET_RECRUITING

Centro de Salud Milladoiro, A Coruña

20259

NOT_YET_RECRUITING

Centenario Hospital Miguel Hidalgo, Aguascalientes

23606

RECRUITING

Tidewater Physicians Multispecialty Group, Newport News

24020

NOT_YET_RECRUITING

Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Ranica (BG)

25160

NOT_YET_RECRUITING

Mackay Memorial Hospital, Taipei

26101

NOT_YET_RECRUITING

MILAN KVAPIL s.r.o., Příbram

26426

NOT_YET_RECRUITING

Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon State

27103

NOT_YET_RECRUITING

Brookview Hills Research Associates LLC, Winston-Salem

27356

NOT_YET_RECRUITING

Nephrologische Gemeinschaftspraxis, Hamann/Bacinovic/Jacobsen, Rotenburg (Wümme)

27704

RECRUITING

Durham Nephrology Associates, Durham

28557

RECRUITING

Lucas Research, Inc., Morehead City

30201

NOT_YET_RECRUITING

Centro de Salud Cartagena Casco Antiguo, Cartagena

30625

NOT_YET_RECRUITING

Medizinische Hochschule Hannover, Hanover

NOT_YET_RECRUITING

Zentrum Für Nieren Hochdruck und Stoffwechselerkrankungen, Hanover

30909

RECRUITING

Masters of Clinical Research, Inc, Augusta

31401

NOT_YET_RECRUITING

Velocity Clinical Research, Savannah, Savannah

32257

NOT_YET_RECRUITING

Internistische Gemeinschaftspraxis in Bünde, Bünde

32720

RECRUITING

Hillcrest Medical Research, DeLand

33012

NOT_YET_RECRUITING

Centro de Salud Naranco, Oviedo

33014

RECRUITING

San Marcus Research Clinic, Inc., Miami Lakes

33024

NOT_YET_RECRUITING

Encore Medical Research, Hollywood

33126

RECRUITING

Finlay Medical Research Corp, Miami

RECRUITING

Total Research Group, LLC, Miami

33511

NOT_YET_RECRUITING

Clinical Research of Brandon LLC, Brandon

33578

NOT_YET_RECRUITING

Florida Kidney Physicians - Riverview/Brandon, Riverview

33604

NOT_YET_RECRUITING

Klinikum Bielefeld, Bielefeld

34761

NOT_YET_RECRUITING

West Orange Endocrinology, Ocoee

35805

RECRUITING

Apogee Clinical Research, Huntsville

37005

NOT_YET_RECRUITING

Centro de Salud de San Juan, Salamanca

37414

NOT_YET_RECRUITING

Southeast Renal Research Institute, Chattanooga

39069

NOT_YET_RECRUITING

Prime Health and Wellness, Fayette

40705

NOT_YET_RECRUITING

Taichung Veterans General Hospital, Taichung

43000

NOT_YET_RECRUITING

Hospital Sultan Idris Shah Serdang, Kajang

44000

NOT_YET_RECRUITING

HOP Hôtel-Dieu, Nantes

44670

NOT_YET_RECRUITING

Unidad de Investigación Clinica y Atencion Medica HEPA SC, Guadalajara

46804

NOT_YET_RECRUITING

Nephrology Associates of Northern Illinois and Indiana - Fort Wayne, Fort Wayne

48341

NOT_YET_RECRUITING

Michigan Kidney Consultants, Pontiac

48504

RECRUITING

Aa Mrc Llc, Flint

50200

NOT_YET_RECRUITING

Maharaj Nakom Chiangmai Hospital, Chiang Mai

50586

RECRUITING

Hospital Kuala Lumpur, Kuala Lumpur

52511

RECRUITING

DaVita Clinical Research Germany GmbH Geilenkirchen, Geilenkirchen

56000

NOT_YET_RECRUITING

Hospital Canselor Tuanku Muhriz, Cheras

60521

NOT_YET_RECRUITING

Nephrology Associates of Northern Illinois and Indiana - Oak Brook, Hinsdale

60590

NOT_YET_RECRUITING

Universitätsklinikum Frankfurt, Frankfurt

60643

RECRUITING

Research by Design, LLC, Chicago

63376

NOT_YET_RECRUITING

Elixia MNA, LLC, City of Saint Peters

66100

NOT_YET_RECRUITING

Azienda Sanitaria Locale 2 Lanciano Vasto Chieti, Chieti

67091

NOT_YET_RECRUITING

HOP Civil, Strasbourg

67214

NOT_YET_RECRUITING

Kansas Nephrology Research Institute, LLC, Wichita

70112

NOT_YET_RECRUITING

LSU Health Sciences Center, New Orleans

70376

NOT_YET_RECRUITING

Robert Bosch Gesellschaft für medizinische Forschung mbH, Stuttgart

71101

NOT_YET_RECRUITING

Northwest Louisiana Nephrology, Shreveport

73601

NOT_YET_RECRUITING

DIKa centrum s.r.o., Havířov

76015

RECRUITING

Arlington Nephrology, Arlington

76401

RECRUITING

Javara Inc.-Stephenville-68996, Stephenville

77004

RECRUITING

Endocrine Associates, Houston

78212

NOT_YET_RECRUITING

Clinical Advancement Center, PLLC, San Antonio

80002

NOT_YET_RECRUITING

Western Nephrology, Arvada, Arvada

83706

NOT_YET_RECRUITING

Boise Kidney and Hypertension, PLLC, Boise

84115

RECRUITING

Utah Kidney Research Institute, Salt Lake City

91307

RECRUITING

Focus Clinical Research, West Hills

91355

RECRUITING

Amicis Research Center - Valencia, Valencia

91356

NOT_YET_RECRUITING

Valiance Clinical Research-Tarzana-68237, Tarzana

91773

RECRUITING

North America Research Institute, San Dimas

91910

NOT_YET_RECRUITING

Sociedad de Metabolismo y Corazón S.C., Veracruz

92801

NOT_YET_RECRUITING

Orange County Clinical Trials, Anaheim

94270

NOT_YET_RECRUITING

HOP Bicêtre, Le Kremlin-Bicêtre

97070

NOT_YET_RECRUITING

Medical Care & Research SA de CV, Mérida

100044

NOT_YET_RECRUITING

Beijing Tsinghua Changgung Hospital, Beijing

210011

NOT_YET_RECRUITING

The Second Affiliated Hospital of Nanjing Medical University, Nanjing

230601

NOT_YET_RECRUITING

The Second Hospital of Anhui Medical University, Hefei

250013

NOT_YET_RECRUITING

Center Hospital of Jinan, Jinan

310014

NOT_YET_RECRUITING

Zhejiang Province People's Hospital, Hangzhou

315010

RECRUITING

Ningbo Second Hospital, Ningbo

330006

NOT_YET_RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

510515

RECRUITING

NanFang Hosptial, Guangzhou

515041

NOT_YET_RECRUITING

Second Hospital Affiliated to Shantou Medical University, Shantou

518035

NOT_YET_RECRUITING

Shenzhen Second People's Hospital, Shenzhen

530000

NOT_YET_RECRUITING

The First People's Hospital of Nanning, Nanning

610041

NOT_YET_RECRUITING

West China Hospital of Sichuan University, Chengdu

644099

NOT_YET_RECRUITING

Yibin Second People's Hospital, Yibin

710061

NOT_YET_RECRUITING

First Affiliated Hospital of Xi'an JiaoTong University, Xi'an

750004

NOT_YET_RECRUITING

General Hospital of Ningxia Medical University, Ningxia

C1060ABN

RECRUITING

CEDIC - Centro de Investigacion Clinica, CABA

C1128AAF

RECRUITING

Mautalen- Salud e Investigacion, CABA

C1180AAX

NOT_YET_RECRUITING

Sanatorio Güemes, Capital Federal

S2000AJU

RECRUITING

Instituto Medico Catamarca - IMEC, Rosario

30220-420

NOT_YET_RECRUITING

Centro de Pesquisa do Hospital Evangélico de Belo Horizonte, Belo Horizonte

72145-450

NOT_YET_RECRUITING

Chronos Pesquisa Clinica, Brasília

36033-318

NOT_YET_RECRUITING

Galileo Medical Research Ltda, Juiz de Fora

15090-000

NOT_YET_RECRUITING

Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto

01228-000

NOT_YET_RECRUITING

Cpquali Pesquisa Clinica Ltda, São Paulo

04038-031

NOT_YET_RECRUITING

Fundação Oswaldo Ramos (Hospital do Rim), São Paulo

04266-010

RECRUITING

CEPIC - Centro Paulista de Investigacao Clinica, São Paulo

05403-000

NOT_YET_RECRUITING

Centro de Pesquisa Clínica de Nefrologia do ICHC, São Paulo

N7T 4X3

RECRUITING

Bluewater Clinical Research, Sarnia

M1B 4Z8

RECRUITING

Heart Health Institute (Scarborough), Scarborough Village

M4G 3E8

NOT_YET_RECRUITING

Sunnybrook Health Sciences Centre, Toronto

M5G 2C4

NOT_YET_RECRUITING

Toronto General Hospital, Toronto

G9A 4P3

NOT_YET_RECRUITING

Diex Recherche (Trois-Rivieres), Trois-Rivières

274 01

NOT_YET_RECRUITING

Hospital Slany, Internal Department, Slaný

01307

NOT_YET_RECRUITING

Universitätsklinikum Carl Gustav Carus Dresden, Dresden

06132

NOT_YET_RECRUITING

Università degli Studi di Perugia, Perugia

00168

NOT_YET_RECRUITING

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma

486-8510

NOT_YET_RECRUITING

Kasugai Municipal Hospital, Aichi, Kasugai

260-8712

NOT_YET_RECRUITING

National Hospital Organization Chibahigashi National Hospital, Chiba, Chiba

300-0028

RECRUITING

Tsuchiura Kyodo General Hospital, Ibaraki, Tsuchiura

234-0054

NOT_YET_RECRUITING

Saiseikai Yokohamashi Nanbu Hospital, Kanagawa, Yokohama

558-8558

RECRUITING

Osaka General Medical Center, Osaka, Osaka

362-8588

RECRUITING

Ageo Central General Hospital, Saitama, Ageo

523-0082

NOT_YET_RECRUITING

Omihachiman Community Medical Center, Shiga, Omihachiman

193-0998

NOT_YET_RECRUITING

Tokyo Medical University Hachioji Medical Center, Tokyo, Hachioji

01000

RECRUITING

Tuanku Fauziah Hospital, Kangar

03650

NOT_YET_RECRUITING

Soltmed Smo, Mexico City

06700

NOT_YET_RECRUITING

Clinica Omega Diabetes, Mexico City

1105 AZ

NOT_YET_RECRUITING

Amsterdam UMC Locatie AMC, Amsterdam

3318 AT

NOT_YET_RECRUITING

Albert SchweitzerZiekenhuis, Dordrecht

5623 EJ

NOT_YET_RECRUITING

Catharina Ziekenhuis, Eindhoven

7909 AA

NOT_YET_RECRUITING

Bethesda Diabetes Research Center, Hoogeveen, Hoogeveen

85-092

RECRUITING

"Centrum Medyczne Hipokrates S.C. Elżbieta I Grzegorz Grześk", Bydgoszcz

32-500

NOT_YET_RECRUITING

American Heart Of Poland Sp. Z O.O., Chrzanów

40-648

RECRUITING

Pro Familia Altera Sp. z o.o., Katowice

91 473

RECRUITING

Pro Salus Sp. z o.o. sp.k., Lodz

00680

NOT_YET_RECRUITING

FDI Clinical Research - Mayagüez, Mayagüez

03312

RECRUITING

The Catholic University of Korea, Eunpyeong St. Mary's Hospital, Seoul

04763

RECRUITING

Hanyang University Medical Center, Seoul

08025

NOT_YET_RECRUITING

C.A.P. Sardenya, Barcelona

08540

RECRUITING

Eap Osona Sud Alt Congost S.L.P. Cap Centelles, Centelles, Barcelona

ML6 0JS

NOT_YET_RECRUITING

University Hospital Monklands, Airdrie

OX16 9AD

RECRUITING

Banbury Cross Health Centre, Banbury

G51 4TF

NOT_YET_RECRUITING

Queen Elizabeth University Hospital, Glasgow

HA3 7LT

RECRUITING

Belmont Health Centre, Harrow

HP11 2QW

RECRUITING

Velocity Clinical Research, High Wycombe, High Wycombe

W6 7HY

RECRUITING

Richford Gate Medical Practice, London

RG1 5AN

RECRUITING

Royal Berkshire Hospital, Reading

SR4 7TP

NOT_YET_RECRUITING

Sunderland Royal Hospital, Sunderland

Sponsors
All Listed Sponsors
lead

Boehringer Ingelheim

INDUSTRY