Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair

NAEnrolling by invitationINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2030

Conditions
Pain, PostoperativeRoot ResorptionPersistent InfectionNecrotic Pulp
Interventions
DRUG

Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol

The studied medicament will be placed onto the floor of the pulp chamber.

DRUG

Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles

The studied medicament will be placed onto the floor of the pulp chamber.

DRUG

chitosan-coated silver nanoparticles

The studied medicament will be placed onto the floor of the pulp chamber.

Trial Locations (1)

Unknown

Faculty of dentistry Ain shams university, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER