NCT06925295 - Using Xe MRI to Guide Radiation Therapy for Lung Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2027

Conditions

Imaging Techniques

Interventions

DRUG

Xenon MRI

MRI with Xenon used for contrast

DIAGNOSTIC_TEST

Pulmonary Function Testing

Pulmonary function testing will include spirometry, lung volumes, DLCO and oscillometry

OTHER

Quality of Life Questionnaire

European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30+QLQ-LC29)

OTHER

Medical Research Council Dyspnea score

modified Medical Research Council Dyspnea score (mMRC Dyspnea)

OTHER

St. George's Respiratory Questionnaire

St. George's Respiratory Questionnaire (SGRQ)

DIAGNOSTIC_TEST

Blood Biomarkers

blood biomarkers of inflammation and injury (e.g. Angiopoetin-2, Interleukin-6, myofibroblast activity, BPD4)

Trial Locations (1)

RECRUITING

University of Iowa, Iowa City

All Listed Sponsors

lead

Sean Fain

OTHER