Alzheimer's Disease Treated With Vagus Nerve Stimulation

NARecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

May 7, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Alzheimer Disease (AD)
Interventions
DEVICE

Vagus Nerve Stimulation

After randomization, VNS is performed for 6 months. The stimulation parameters will be 30 Hz and 250 μs, the maximum tolerable current is selected according to the patients' adverse reactions (dizziness, palpitations, abnormal sensations, local pain, etc.), and the recommended treatment intensity is 0.8 mA.

DEVICE

Sham Vagus Nerve Stimulation

After randomization, sham vagus nerve stimulation VNS treatment is performed for 6 months. The stimulation parameters will be 30 Hz, 250 μs, and the treatment intensity will be 0 mA.

Trial Locations (1)

100070

RECRUITING

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
lead

Beijing Municipal Administration of Hospitals

OTHER_GOV