74
Participants
Start Date
May 7, 2025
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2027
Vagus Nerve Stimulation
After randomization, VNS is performed for 6 months. The stimulation parameters will be 30 Hz and 250 μs, the maximum tolerable current is selected according to the patients' adverse reactions (dizziness, palpitations, abnormal sensations, local pain, etc.), and the recommended treatment intensity is 0.8 mA.
Sham Vagus Nerve Stimulation
After randomization, sham vagus nerve stimulation VNS treatment is performed for 6 months. The stimulation parameters will be 30 Hz, 250 μs, and the treatment intensity will be 0 mA.
RECRUITING
Beijing Tiantan Hospital, Beijing
Beijing Municipal Administration of Hospitals
OTHER_GOV