Implementing Polygenic Risk Scores for Breast Cancer Prevention: a Feasibility Study

NANot yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 9, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

May 30, 2026

Conditions
Breast Cancer
Interventions
DIAGNOSTIC_TEST

Integrated PRS-Enhanced Breast Cancer Risk Assessment (CanRisk model)

Standard genetic counseling followed by a blood draw (0.5 mL) for DNA extraction. The sample is processed using a high-throughput SNP genotyping platform, and the PRS, based on 313 SNPs, is calculated and integrated into the CanRisk model for refined breast cancer risk stratification.

All Listed Sponsors
collaborator

Catholic University of the Sacred Heart

OTHER

lead

Boccia Stefania

OTHER