Comparative Efficacy of 3L and 2L Integrated Techniques for Gynecologic Cancer-related Lower Extremity Lymphedema: a Retrospective Study

CompletedOBSERVATIONAL
Enrollment

125

Participants

Timeline

Start Date

April 1, 2018

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions
Gynecologic Cancer-related Lower Extremity LymphedemaLymphedema
Interventions
PROCEDURE

VLNT(Vascularized Lymph Node Transfer)

VLNT is a physiologic surgical procedure in which vascularized lymph nodes are harvested from a donor site (e.g., groin or submental region) and transplanted to the affected limb to restore lymphatic drainage. The transferred lymph nodes are anastomosed to recipient vessels to ensure perfusion, aiming to reconstruct lymphatic flow and reduce lymphedema-related swelling and fibrosis.

PROCEDURE

LVA(Lymphaticovenular Anastomosis)

LVA is a supermicrosurgical technique designed to improve lymphatic drainage by creating anastomoses between functional lymphatic vessels and nearby venules. Under high magnification, lymphatic vessels (typically \<0.8 mm) are identified and connected to subdermal venules to bypass obstructed lymphatic pathways, facilitating improved lymph flow and symptom relief in patients with early-stage lymphedema.

PROCEDURE

LS(Liposuction)

LS is a volume-reduction procedure used in the management of advanced lymphedema characterized by fibroadipose tissue hypertrophy. Tumescent liposuction is performed to remove excess subcutaneous adipose tissue, thereby reducing limb volume and improving limb contour. This procedure is often combined with physiologic surgical techniques for optimal long-term outcomes.

Trial Locations (1)

563003

Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi

All Listed Sponsors
lead

Zunyi Medical College

OTHER

NCT06920732 - Comparative Efficacy of 3L and 2L Integrated Techniques for Gynecologic Cancer-related Lower Extremity Lymphedema: a Retrospective Study | Biotech Hunter | Biotech Hunter