824
Participants
Start Date
July 9, 2025
Primary Completion Date
May 31, 2036
Study Completion Date
May 31, 2036
Elranatamab
Elranatamab is given to arm B patients in association with lenalidomide (for consolidation) and arm D patients in monotherapy (for maintenance) as experimental arms
Lenalidomide (Revlimid®)
In association with daratumumab, bortezomib and dexamethasone (Arm A), in association with elranatamab (Arm B), in monotherapy (Arm C)
Daratumumab SC (Darzalex)
Daratumumab is given in association with bortezomib, lenalidomide and dexamethasone in induction therapy (all patients) and consolidation arm A
Autologous Stem Cell Transplantation
ASCT is performed in consolidation for Arm A patients after induction therapy with D-VRD
Bortezomib (Velcade®)
Bortezomib is given in associtaion with daratumumab, lenalidomide and dexamethasone in induction (all patients) and consolidation Arm A
Dexamethasone
Dexamethasone is given in association with daratumumab, bortezomib and lenalidomide in induction (all patients) and consolidation Arm A
NOT_YET_RECRUITING
Amiens, Amiens
NOT_YET_RECRUITING
CHU Angers, Angers
NOT_YET_RECRUITING
Ch Annecy Genevois, Annecy
NOT_YET_RECRUITING
Centre Hospitalier d'Argenteuil Victor Dupouy, Argenteuil
ACTIVE_NOT_RECRUITING
Centre Hospitalier H. Duffaut, Avignon
NOT_YET_RECRUITING
Centre hospitalier de la Côte Basque, Bayonne
ACTIVE_NOT_RECRUITING
CHU Besançon, Besançon
NOT_YET_RECRUITING
Centre Hospitalier Simone Veil, Blois
NOT_YET_RECRUITING
Hôpital Avicenne, Bobigny
NOT_YET_RECRUITING
CHU Bordeaux - Hopital Haut Lévêque - Centre F. Magendi, Bordeaux
NOT_YET_RECRUITING
CH Fleyriat, Bourg-en-Bresse
NOT_YET_RECRUITING
CHRU Brest - Hôpital A. Morvan, Brest
NOT_YET_RECRUITING
CHU Caen - Côte de Nacre, Caen
NOT_YET_RECRUITING
Centre Hospitalier William Morey, Chalon-sur-Saône
NOT_YET_RECRUITING
CHMS Centre Hospitalier Métropole Savoie, Chambéry
NOT_YET_RECRUITING
Hopital Louis Pasteur, Chartres
NOT_YET_RECRUITING
Hôpital d'Instruction des Armées Percy, Clamart
NOT_YET_RECRUITING
Chu Estaing, Clermont-Ferrand
NOT_YET_RECRUITING
Centre Hospitalier Sud Francilien, Corbeil-Essonnes
NOT_YET_RECRUITING
CHU Henri Mondor, Créteil
NOT_YET_RECRUITING
CHU Dijon, Dijon
NOT_YET_RECRUITING
Institut de cancérologie de Bourgogne, Dijon
NOT_YET_RECRUITING
Centre Hospitalier de Dunkerque, Dunkirk
NOT_YET_RECRUITING
CHU de Grenoble, Grenoble
NOT_YET_RECRUITING
CHU de la Réunion Site SUD (Terre Sainte), La Réunion
RECRUITING
CHD Vendée, La Roche-sur-Yon
NOT_YET_RECRUITING
Hopital Monod, Le Havre
NOT_YET_RECRUITING
CH Le mans, Le Mans
NOT_YET_RECRUITING
CHRU Hôpital Claude Huriez, Lille
NOT_YET_RECRUITING
Centre Hospitalier Universitaire (CHU) de Limoges, Limoges
NOT_YET_RECRUITING
Centre Hospitalier Lyon Sud, Lyon
NOT_YET_RECRUITING
Grand Hopital Est Francilien (GHEF) Site de Meaux, Meaux
NOT_YET_RECRUITING
Hôpital de Mercy (CHR Metz-Thionville), Metz
NOT_YET_RECRUITING
Centre de Recherche Clinique / GHT des Landes, Mont-de-Marsan
NOT_YET_RECRUITING
Hopital Saint Eloi - CHU Montpellier, Montpellier
NOT_YET_RECRUITING
Hôpital E. Muller, Mulhouse
NOT_YET_RECRUITING
CHRU Hôpitaux de Brabois, Nancy
NOT_YET_RECRUITING
CHRU Hôtel Dieu, Nantes
NOT_YET_RECRUITING
Hôpital Archet 1, Nice
NOT_YET_RECRUITING
CHU Carémeau, Institut de Cancérologie du Guard, Nîmes
NOT_YET_RECRUITING
CHR Orléans, Orléans
NOT_YET_RECRUITING
CHU Hôpital Saint Antoine, Paris
NOT_YET_RECRUITING
Hôpital Cochin, Paris
NOT_YET_RECRUITING
Hôpital Necker, Paris
NOT_YET_RECRUITING
Hôpital Saint Louis, Paris
NOT_YET_RECRUITING
La Pitié Salpêtrière, Paris
NOT_YET_RECRUITING
CH Saint Jean, Perpignan
NOT_YET_RECRUITING
Centre Hospitalier de Perigueux, Périgueux
NOT_YET_RECRUITING
CHU Poitiers - Pôle régional de Cancérologie, Poitiers
NOT_YET_RECRUITING
Centre hospitalier René Dubost, Pontoise
NOT_YET_RECRUITING
Centre Hospitalier de Quimper Cornouaille, Quimper
NOT_YET_RECRUITING
Hôpital Robert Debré, Reims
NOT_YET_RECRUITING
CHRU Hôpital de Pontchaillou, Rennes
NOT_YET_RECRUITING
Centre Henri Becquerel, Rouen
NOT_YET_RECRUITING
Centre Hospitalier Saint Brieuc, Saint-Brieuc
NOT_YET_RECRUITING
Institut de Cancérologie Lucien Neuwirth, Saint-Priest
NOT_YET_RECRUITING
Centre Hospitalier de Saint-Quentin, Saint-Quentin
NOT_YET_RECRUITING
CHU Strasbourg, Strasbourg
NOT_YET_RECRUITING
Centre hospitalier, Tarbes
NOT_YET_RECRUITING
Pôle IUCT Oncopole CHU, Toulouse
NOT_YET_RECRUITING
CHRU Hôpital Bretonneau - Centre Henry Kaplan, Tours
NOT_YET_RECRUITING
CH Bretagne Atlantique Vannes et Auray - P. Chubert, Vannes
NOT_YET_RECRUITING
CHV André Mignot - Université de Versailles, Versailles
NOT_YET_RECRUITING
Gustave Roussy, Villejuif
Collaborators (1)
Pfizer
INDUSTRY
Intergroupe Francophone du Myelome
NETWORK