PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

July 31, 2025

Study Completion Date

October 31, 2025

Conditions
Postpartum Hypertension (PPHT)
Interventions
DRUG

Labetalol

Labetalol is a beta-blocker commonly used to manage hypertension in pregnancy and postpartum. In this study, oral labetalol will be initiated at 200mg twice or three times daily and adjusted up to 2400 mg/day as needed for blood pressure control.

DRUG

Nifedipine

Nifedipine is a calcium channel blocker commonly used to manage hypertension in pregnancy and postpartum. In this study, oral extended-release nifedipine will be initiated at 30mg once daily and adjusted up to 120mg/day as needed for blood pressure control.

All Listed Sponsors
lead

University of California, Los Angeles

OTHER