The Ameliorative Effect of C-Kit (+) Hepatic Endothelial Cells With Mertk Deficiency on Nonalcoholic Steatohepatitis

Active, not recruitingOBSERVATIONAL
Enrollment

6

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

May 31, 2026

Conditions
Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions
PROCEDURE

Ultrasonund-guided percutaneous liver biopsy

All patients completed blood routine, coagulation function and liver biochemical indexes before surgery, and informed the patients and their families about the purpose and risks of surgery, and signed an informed consent. During the procedure, the patient was placed in the left lateral decubitus position. After locating by ultrasound and routine disinfection, 0.5% lidocaine was used for local anesthesia. Under the guidance of ultrasound, a 16G disposable biopsy needle (SC1620) was inserted into the liver parenchyma, and the biopsy gun was started and fired for sampling. The removed liver tissue was fixed in 4% formaldehyde solution and sent to the pathology department. The patient's puncture site was disinfected and covered with sterile dressing, and the abdominal band was bandaged. The patients were instructed to stay in bed for 24 hours after operation, closely observe whether there was pain and bleeding after operation, and monitor electrocardiogram for 24 hours.

Trial Locations (1)

200120

Shanghai East Hospital (East Hospital Affiliated To Tongji University), Shanghai

All Listed Sponsors
collaborator

National Natural Science Foundation of China

OTHER_GOV

lead

Shanghai East Hospital

OTHER

NCT06913699 - The Ameliorative Effect of C-Kit (+) Hepatic Endothelial Cells With Mertk Deficiency on Nonalcoholic Steatohepatitis | Biotech Hunter | Biotech Hunter