Hybrid Closed-Loop System in Neurosurgical Perioperative Hyperglycemia: An Open RCT

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

April 15, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

August 31, 2027

Conditions
T2DM Patients With Traumatic Brain Injury
Interventions
DEVICE

Hybrid Closed-Loop Artificial Pancreas System

The total daily insulin requirement is calculated as 0.3 - 0.6 U/(kg·d) according to patient's weight. The system automatically adjusts the basal rate during operation. Nurses enter bolus dose orders in AAPS software as directed by physicians. Blood glucose is monitored via continuous glucose monitoring and 4 daily fingerstick measurements (fasting and 2 hours after each meal).

Trial Locations (1)

030000

RECRUITING

Shanxi Bethune Hospital, Taiyuan

All Listed Sponsors
lead

Shanxi Bethune Hospital

OTHER