Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

RecruitingOBSERVATIONAL
Enrollment

2,000

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

April 30, 2035

Study Completion Date

April 30, 2035

Conditions
AmputationAmputation of Lower LimbAmputation of Upper LimbAmputation, Limb LossAmputation, Traumatic/SurgeryCryo Analgesia
Interventions
DEVICE

cryoablation

Cryoanalgesia, also known as Cryoablation, Cryoneurolysis, or Cryonerve Block, has been used for decades to treat chronic pain and has recently been employed for the management of Phantom Limb Pain. Cryoanalgesia involves the use of a probe to apply extreme cold (approximately -70◦C) to induce reversible axonal injury and Wallerian degeneration to produce a temporary conduction block that is sustained until regeneration of the axon and sensation is restored, typically weeks to months later.

Trial Locations (3)

53226

RECRUITING

Medical College of Wisconsin/Froedtert Hospital, Milwaukee

01201

RECRUITING

Berkshire Medical Center, Pittsfield

03101

RECRUITING

Elliot Hospital, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AtriCure, Inc.

INDUSTRY