124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome

PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

March 31, 2027

Study Completion Date

May 31, 2027

Conditions
Lumbar Spinal StenosisCarpal Tunnel Syndrome (CTS)Cardiac Amyloidosis
Interventions
DRUG

124I-evuzamitide

124I-evuzamitide is an iodine-124 (124I) labeled 45 L-amino acid peptide (also known as p5+14) suitable for single dose PET/CT imaging. The peptide binds many forms of amyloid through multivalent electrostatic interactions with the amyloid fibril and with the ubiquitous amyloid-associated hypersulfated heparan sulfate proteoglycans.

Trial Locations (1)

37920

University of Tennessee Graduate School of Medicine, Knoxville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Attralus, Inc.

INDUSTRY

lead

University of Tennessee Graduate School of Medicine

OTHER

NCT06907849 - 124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome | Biotech Hunter | Biotech Hunter