Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia

NARecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

May 12, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
Nociceptive PainPain, PostoperativeAnalgesia, PostoperativeAnesthesia Recovery PeriodOpioid Use
Interventions
PROCEDURE

NOL (Nociception Level Index)

Elective surgery in patients having trauma and orthopedic surgery with a combination of general and regional anesthesia. Opioid titration is guided by NOL during general anesthesia in the experimental arm.

OTHER

Control (Standard treatment)

Opioid administration (sufentanil) guided according to standard clinical practice of the attending anesthesiologist

Trial Locations (1)

20246

RECRUITING

Department of Anesthesiology; Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg Eppendorf, Hamburg

All Listed Sponsors
lead

Universitätsklinikum Hamburg-Eppendorf

OTHER