Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection

NARecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

November 25, 2024

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
Liver Tumor; SurgeryPrimary Liver Tumor, Metastatic LiverPrimary Liver CancerLiver ResectionBenign Liver Tumor
Interventions
DEVICE

High stroke volume variation group

Anesthesiologists will perform methods to achieve and maintain SVV at 13-20% during liver parenchymal transection (fluid restrictive phase). Central venous pressure monitoring will be concealed with drapes, and the room anesthesiologist will use SVV for guiding fluid management only during parenchymal transection phase. If SVV exceeds 20%, a balanced salt crystalloid will be administered in the minimal amount necessary to reduce the SVV to below 20%.

Trial Locations (1)

50200

RECRUITING

Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiang Mai

All Listed Sponsors
collaborator

Chiang Mai University

OTHER

lead

Warangkana Lapisatepun

OTHER