Endoscopic Resection for Small Rectal Neuroendocrine Tumors

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

October 31, 2027

Conditions
Rectal Neuroendocrine Tumor
Interventions
PROCEDURE

mEMR-C procedure

A transparent cap with an inner groove (MH-593; Olympus, Tokyo, Japan) was attached to the forward-viewing colonoscope. After the endoscope was inserted into the rectum, a crescent-shaped electrosurgical snare was passed through the sheath and looped along the inner groove of the cap. Submucosal injections were not required in this method. The tumor was suctioned into the cap and grasped by tightening the snare. After confirming the appropriate snare placement, both the tumor and overlying mucosa were resected using electric cautery (Endocut Q, effect 2, VIO 200D; ERBE, Tübingen, Germany), and the resected tumor was sent for pathological examination. Endoscopic examination was repeated without a transparent cap to evaluate the wound carefully in cases of perforation or bleeding and to ensure the absence of residual tumor tissues. If there was spurting or active bleeding, hot forceps were used to stop the bleeding.

PROCEDURE

mEMR-L procedure

First, install the ligation device (provided by Jiangsu Gerrit) at the front end of the endoscope. After inserting the endoscope into the rectum, suck the lesion into the ligation device, release the ligator to ligate the lesion. Then, use a snare to resect the lesion below the ligator. Finally, uniformly suture the wound surface with metal clips.

All Listed Sponsors
lead

Guangdong Provincial People's Hospital

OTHER

NCT06901856 - Endoscopic Resection for Small Rectal Neuroendocrine Tumors | Biotech Hunter | Biotech Hunter