400
Participants
Start Date
July 14, 2025
Primary Completion Date
August 31, 2027
Study Completion Date
December 31, 2027
Reprieve System
The Reprieve System is a hospital bedside fluid management console designed to provide personalized and automated infusion of the IV diuretic furosemide and physiological saline in response to the patient's real-time urine output to safely and rapidly decongest patients suffering from Acute Decompensated Heart Failure.
furosemide infusion
Participants randomized to ODT will be treated with guided diuretic titration, as recommended in the ESC guidelines on diuretic therapy
RECRUITING
Atrium Health Wake Forest Baptist Medical Center, Winston-Salem
NOT_YET_RECRUITING
Moses H. Cone Memorial Hospital, Greensboro
NOT_YET_RECRUITING
Duke University, Durham
RECRUITING
Hospital Ramon y Cajal, Madrid
RECRUITING
Prisma Health Greenville Memorial Hospital, Greenville
RECRUITING
Northeast Georgia Medical Center, Gainesville
RECRUITING
University of Florida, Gainesville
RECRUITING
University of Mississippi, Jackson
RECRUITING
Ohio State University Hospital, Columbus
RECRUITING
UH Cleveland Medical Center, Cleveland
RECRUITING
University Hospital Cleveland, Cleveland
RECRUITING
Lindner Center at Christ Hospital, Cincinnati
RECRUITING
University Hospital Wroclaw, Wroclaw
RECRUITING
Clínico Universitario de Valencia, Valencia
RECRUITING
Hospital General Valencia, Valencia
RECRUITING
Corewell William Beaumont University Hospital, Royal Oak
RECRUITING
Trinity Health Ann Arbor Hospital, Ann Arbor
RECRUITING
Minneapolis Heart Institute, Minneapolis
RECRUITING
St. Louis VA, St Louis
RECRUITING
Washington University, St Louis
RECRUITING
Medical University of Lodz, Lodz
RECRUITING
Oklahoma Heart Hospital, Oklahoma City
RECRUITING
Baylor Scott and White, Dallas
RECRUITING
Baylor College of Medicine Ben Taub Hospital, Houston
RECRUITING
University of California Irvine, Irvine
RECRUITING
UW Harborview, Seattle
RECRUITING
University of Pennsylvania, Philadelphia
Reprieve Cardiovascular, Inc
INDUSTRY