Comparison of Safety and Efficacy Between PIEB and CEI for Labour Epidural Analgesia

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

August 30, 2025

Study Completion Date

December 30, 2025

Conditions
Analgesia, Epidural
Interventions
PROCEDURE

Continuos epidural infusion

"This group of parturient will be inserted epidural catheter at L3/L4 or L4/L5 depending on anaesthetist-in-charge justification, epidural catheter will be kept 4-5 cm in epidural space and anchored with adhesive tape. Similarly, a test dose of LA Lignocaine 2% 2ml will be given after epidural insertion. Infusion tubing will be primed in advance. Epidural catheter will be connected to epidural cocktail (Bupivacaine 0.1% + Fentanyl 2mcg/ml in 50ml mixture) with the protocol as below: (directly extracted from Malaysia Pain management in Obstetrics and Gynaecology Procedure Guideline 2023)~* Loading dose 10 ml~* Continuous infusion: 10ml/hour"

PROCEDURE

Programmed intermittent epidural bolus

"This group patient will be inserted epidural catheter at L3/L4 or L4/L5 depending on anaesthetist-in-charge justification, epidural catheter will be kept 4-5 cm in epidural space and anchored with adhesive tape. A test dose of LA Lignocaine 2% 2ml will be given after epidural insertion. CADD-Solis infusion tubing will be primed in advance. Epidural catheter will be connected to epidural cocktail (Ropivacaine 0.05% + Fentanyl 2mcg/ml in 100ml mixture) with the protocol as below:~* Loading dose: 10ml~* Intermittent bolus: 10ml, bolus interval 1 hour, next bolus 1 hour~* PCEA dose: 10ml, lockout interval 10 minutes"

Trial Locations (1)

16150

Hospital Pakar Universiti Sains Malaysia, Kubang Kerian

All Listed Sponsors
lead

Hospital Universiti Sains Malaysia

OTHER