Long-term Safety of Nipple Sparing Mastectomy in Women With GPV in Breast Cancer

RecruitingOBSERVATIONAL
Enrollment

4,700

Participants

Timeline

Start Date

February 1, 2025

Primary Completion Date

February 1, 2027

Study Completion Date

February 1, 2028

Conditions
Breast Cancer Surgery
Interventions
PROCEDURE

Nipple Sparing Mastectomy (NSM)

Nipple sparing mastectomy (NSM) is a surgical procedure which removes all macroscopic breast glandular tissue while retaining the skin as well as the nipple areola complex.

PROCEDURE

Skin-Sparing Mastectomy (SSM)

Skin sparing mastectomy (SSM) is a procedure that removes the nipple and areola complex along with all visible macroscopic breast glandular tissue.

PROCEDURE

Total (Simple) Mastectomy

Total (Simple) Mastectomy is a traditional mastectomy approach that removes the breast glandular tissue with a large overlying area of skin including the nipple and areola complex to allow for flat closure.

Trial Locations (12)

2030

ACTIVE_NOT_RECRUITING

Ziekenhuis Aan de Stroom, Antwerp

10065

NOT_YET_RECRUITING

Memorial Sloan Kettering Cancer Center (MSKCC), New York

06510

RECRUITING

Yale University, New Haven

02115

NOT_YET_RECRUITING

Brigham and Women's Hospital - Dana-Farber Brigham Cancer Center, Boston

19104-6205

RECRUITING

University of Pennsylvania, Philadelphia

Unknown

NOT_YET_RECRUITING

University of Melbourne, Peter MacCallum Cancer Center, Melbourne

NOT_YET_RECRUITING

Women's College Hospital, University of Toronto, Toronto

NOT_YET_RECRUITING

Champalimaud Foundation, University of Lisbon, Lisbon

T2N 4N1

RECRUITING

University of Calgary, Calgary

L8L 2X2

RECRUITING

Hamilton Health Sciences, Hamilton

H3T1E2

RECRUITING

Jewish General Hospital, Montreal

G1S 4L8

RECRUITING

CHU de Quebec Université laval, Québec

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cancer Research Society

OTHER

collaborator

Quebec Breast Cancer Foundation

OTHER

lead

Sir Mortimer B. Davis - Jewish General Hospital

OTHER