105
Participants
Start Date
March 20, 2025
Primary Completion Date
June 10, 2025
Study Completion Date
June 11, 2025
Placebo (Normal Saline)
Patients in this group will receive an intravenous (IV) injection of normal saline before surgery. This serves as a control group to compare the efficacy of active treatment groups in preventing postoperative nausea and vomiting.
Ondansetron (Zofran)
Patients in this group will receive a single intravenous (IV) dose of Ondansetron 4 mg before surgery. Ondansetron is a selective 5-HT3 receptor antagonist commonly used to prevent nausea and vomiting associated with anesthesia and surgery.
Dexamethasone
Patients in this group will receive a single intravenous (IV) dose of Dexamethasone 8 mg before surgery. Dexamethasone is a corticosteroid with anti-inflammatory properties that has been shown to reduce the incidence of PONV by modulating inflammatory pathways and neuroreceptor activity.
Federal Government Polyclinic (Postgraduate Medical Institute), Islamabad
Federal Government Polyclinic (Postgraduate Medical Institute)
OTHER
Hafiz Muhammad Hamza
OTHER