83
Participants
Start Date
July 15, 2025
Primary Completion Date
April 30, 2027
Study Completion Date
April 30, 2027
Behavioral task of social perception (stage 1)
Patients with Parkinson disease and healthy volunteer are engaged in a social perception behavioral task.
Functional magnetic resonance imaging: 3 Tesla magnetic resonance imaging (stage 2)
"Patients with Parkinson disease and healthy volunteer are assessed by functional magnetic resonance imaging while they are engaged in a social perception behavioral task.~2 times for patients with Parkinson disease (during ON-levodopa and OFF-levodopa) Once for healthy volunteer"
Neurological and neuropsychological assessments
Patients with Parkinson disease and healthy volunteer will undergo a neurological and neuropsychological assessment with several evaluations: weight, height, medical history, global cognitive performance (MoCA and BREF score), apathy (LARS score), depression (BDI-II score), social cognition (mini-SEA), and quality of life (PDQ39 self-questionnaire).
Neurological assessments of Parkinson's disease symptoms and caregiver burden
Patients with Parkinson disease will undergo a neurological assessment of motor and non-motor symptoms of Parkinson's disease (MDS-UPDRS III \& IV scale and MDS-NMS scale) and caregiver burden (Zarit scale).
RECRUITING
Service de neurologie - troubles du mouvement et pathologies neuromusculaires, Hôpital neurologique Pierre Wertheimer/GHE, Bron
Hospices Civils de Lyon
OTHER