14
Participants
Start Date
September 14, 2024
Primary Completion Date
August 31, 2025
Study Completion Date
August 31, 2025
repetitive transcranial magnetic stimulation (Magstim Super Rapid stimulator, The Magstim Company Ltd, Whitland, UK)
The paradigm will be applied over the dominant cerebral hemisphere for 10 minutes (600 pulses) over the dominant pharyngeal motor cortex capped at 120% of pharyngeal resting motor threshold.
pharyngeal electrical stimulation (Digitimer model DS7; Welwyn-Garden City, Herts, UK)
The PES (0.2-ms pulses, 280 V) was delivered at a set frequency (5 Hz), intensity (75% of maximal tolerated), and duration (10 minutes), which have been reported as the most effective parameters for PES.
sham repetitive transcranial magnetic stimulation(Magstim Super Rapid stimulator, The Magstim Company Ltd, Whitland, UK)
Sham rTMS is delivered with the coil tilted to its side at 90 degrees and with the identical stimulation conditions as active 1 Hz rTMS.
sham pharyngeal electrical stimulation (Digitimer model DS7; Welwyn-Garden City, Herts, UK)
For sham pharyngeal stimulation, the same method including the insertion of the catherter will be employed without actual electrical stimulation.
RECRUITING
University of Manchester, Manchester
University of Manchester
OTHER