48
Participants
Start Date
February 18, 2025
Primary Completion Date
April 30, 2026
Study Completion Date
April 30, 2026
Short-term continuous normal meal replacement
The normal meal replacement intake is calculated at 25kcal/kg body weight per person per day, with the calorie ratio for breakfast, lunch and dinner being 1:2:2. A meal replacement diet is given for 2 consecutive weeks.
Short-term continuous low-valine meal replacements
The low valine meal replacement intake is calculated at 25kcal/kg body weight per person per day, with the calorie ratio for breakfast, lunch and dinner being 1:2:2. A meal replacement diet is given for 2 consecutive weeks.
Long-term intermittent normal meal replacement
The normal meal replacement intake was calculated at 25 kcal/kg body weight per person per day, with the calorie distribution ratio of 1:2:2 for breakfast, lunch and dinner. A meal replacement diet was used for 2 consecutive days per week for 16 consecutive weeks.
Long-term intermittent low valine meal replacement
The low valine meal replacement intake was calculated at 25 kcal/kg body weight per person per day, with the calorie distribution ratio of 1:2:2 for breakfast, lunch and dinner. A meal replacement diet was used for 2 consecutive days per week for 16 consecutive weeks.
RECRUITING
Zhongshan Hospital, Fudan University, Shanghai
Shanghai Zhongshan Hospital
OTHER