Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.

PHASE3RecruitingINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

January 5, 2025

Primary Completion Date

April 1, 2025

Study Completion Date

November 1, 2025

Conditions
HalitosisMouth DiseasePlaque Induced Gingival DiseaseBleeding GumPeridontal Disease
Interventions
DRUG

resveratrol mouthwash

"the participants where instruct to rinse their mouth twice daily with 10 ml of assigned mouthwash for 60 seconds for 7 days. There is currently no published research on the use of resveratrol as a mouthwash for halitosis treatment.~This study aims to fill this gap by evaluating its effectiveness in reducing oral malodor through antibacterial action and the potential of volatile sulfur compounds ( VSCs)"

DRUG

Chlorhexidine mouthwash (0.2%)

The second group will given chlorhexidine 0.2% mouthwash as an active comparator, and will asked to rinse with 10 ml of undiluted mouthwash for 60 seconds twice per day for 7 days, and will instructed to refrain from eating and drinking for 30 min after rinsing.

DRUG

Placebo

the third group will given the nonactive control, distilled water, and will be asked to rinse with 10 ml of undiluted mouthwash for 60 seconds twice daily for 7 days and will be instructed to refrain from eating and drinking for 30 min after rinsing.

Trial Locations (1)

10047

RECRUITING

Mustansiriyah University, Baghdad

All Listed Sponsors
lead

Al-Mustansiriyah University

OTHER