Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S

NANot yet recruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

March 20, 2025

Primary Completion Date

September 20, 2025

Study Completion Date

September 30, 2025

Conditions
Polycystic Ovary Syndrome
Interventions
OTHER

Intermittent fasting diet

Women in the first experimental group will follow an intermittent fasting diet, where they eat for 8 hours and fast for 16. They can skip breakfast or have an early dinner. Meals will include 500-800 calories of high-fiber and protein-rich foods. Participants can start with 2-3 fasts per week and increase gradually. They must drink 2-3L of water daily and can consume zero-calorie beverages. Weekly assessments will track progress.

OTHER

Resistive exercise program

Women in the second experimental group will receive medical treatment and follow an 8-week resistive exercise program (30 min, 5 days/week). Exercises target the upper body, abdomen, and lower limbs, starting with a 10-min warm-up, followed by 30 min of resistance training (biceps curls, triceps exercises, chest press, plank, crunches, squats, lunges, hamstring, and quadriceps curls), and ending with a 10-min cool-down. Repetitions are logged weekly for assessment.

DRUG

Medical treatment

Each woman in the three groups will receive medical treatment (metformin tablets) for eight weeks and the dose will prescribed by the gynecologist during the first visit. Patients will be asked to attend the clinic each month for routine monitoring.

Trial Locations (1)

Unknown

Mashtoul Elsouq general Hospital, ‘Ezbet el-Sharika el-Miṣrîya

All Listed Sponsors
lead

Cairo University

OTHER

NCT06882291 - Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S | Biotech Hunter | Biotech Hunter