The Locus Coeruleus, Norepinephrine and Cognitive Aging

NAActive, not recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

January 1, 2026

Study Completion Date

January 1, 2026

Conditions
Alzheimer Disease
Interventions
DEVICE

t-VNS transcutaneous auricular vagus nerve stimulator

An investigator will clip the the transcutaneous auricular vagus nerve stimulator (taVNS) to the outer ear, and apply electrical current to modulate the activity of the vagus nerve. During this process, the investigator will monitor pupil size and heart rate to determine whether either of these variables is affected by vagus nerve stimulation.

Trial Locations (1)

14850

Cornell University, Ithaca

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cornell University

OTHER

NCT06880510 - The Locus Coeruleus, Norepinephrine and Cognitive Aging | Biotech Hunter | Biotech Hunter