The Effect of CUGP Fluid Management in Patients With Sepsis or Septic Shock

NARecruitingINTERVENTIONAL
Enrollment

118

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

May 31, 2026

Conditions
Sepsis
Interventions
DEVICE

critical ultrasonography

In the CUGP group, attending physicians utilized a designed fluid management strategy guided by ultrasonographic evaluation of the inner diameter of IVC, ejection fraction (EF) value and passive leg raising-induced changes in VTI (ΔVTI). This ultrasonographic assessment was performed by a team of trained critical ultrasonography physicians at enrollment, 1 hour, 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours thereafter, respectively. Additionally, patients did not preclude the concurrent use of conventional hemodynamic monitoring methods. At each of these time points, attending physicians would make comprehensive decisions on fluid management based on the results of ultrasonographic evaluation, along with other monitoring methods. The researcher recorded the basis of decisions, disposal strategy and outcomes.

Trial Locations (1)

430030

RECRUITING

Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
lead

Shusheng Li

OTHER