NCT06876038View on ClinicalTrials.gov

Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

May 31, 2028

Conditions
Oral CancerOral Cavity CancerOral LeukoplakiaOral Lichen PlanusOral Squamous Cell Carcinoma
Interventions
DRUG

5-Amino Levulinic Acid

5-ALA (Gleolan) orally (20 mg/kg BW 5-ALA HCl) 2 to 4 hours prior to undergoing image-guided SITOS-based PDT treatment

Trial Locations (2)

202002

Jawaharlal Nehru Medical College, AMU, Aligarh

Unknown

Karkinos Healthcare Hospitals, Ernākulam

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

University of Arizona

OTHER

collaborator

Aligarh Muslim University

OTHER

collaborator

Karkinos Healthcare Hospitals Ernakulam, Kerala, India

UNKNOWN

collaborator

National Cancer Institute (NCI)

NIH

lead

University of Massachusetts, Boston

OTHER