A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

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The First Affiliated Hospital, Sun Yat-sen University, Guangzhou

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Cancer Hospital Chinese Academy of Medical Sciences. Shenzhen Center, Shenzhen

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Queen Mary Hospital, Hksar

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Queen Mary Hospital, Hksar

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Tri-Service General Hospital, Taipei City

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Taipei Medical University Shuang Ho Hospital, New Taipei City

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National Cheng Kung University Hospital, Tainan City

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Local Institution - 0151, Budapest

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Medizinische Universität Wien, Vienna

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UZ Brussel, Brussels

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Országos Korányi Pulmonológiai Intézet, Budapest

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Cliniques universitaires Saint-Luc, Brussels

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Local Institution - 0673, Vienna

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Hospital Universitario Austral, Pilar

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Multiprofile Hospital for Active Treatment Serdika EOOD, Sofia

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Sanatorio Plaza, Rosario

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Tamworth Hospital, North Tamworth

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Canberra Hospital, Canberra

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Orange Hospital, Orange

NOT_YET_RECRUITING

Local Institution - 0157, Tatabánya

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UZ Leuven, Leuven

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Northern Hospital, Melbourne

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Frankston Hospital, Frankston

NOT_YET_RECRUITING

Local Institution - 0144, Gyöngyös - Mátraháza

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Jessa Ziekenhuis, Hasselt

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Latrobe Regional Health, Traralgon

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Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège

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Kepler Universitätsklinikum, Linz

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Princess Alexandra Hospital, Brisbane

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MBAL Uni Hospital, Panagyurishte

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Klinikum Wels-Grieskirchen GmbH, Wels

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Lyell McEwin Hospital, Elizabeth Vale

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Trakia Hospital, Stara Zagora

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Joondalup Health Campus, Joondalup

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Complex Oncology Center - Ruse EOOD, Rousse

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Local Institution - 0593, Kaposvár

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Medizinische Universität Graz, Graz

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Local Institution - 0143, Farkasgyepű

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Kantonsspital Münsterlingen - Spital Thurgau AG, Münsterlingen

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AZ Maria Middelares, Ghent

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Petz Aladar Egyetemi Oktato Korhaz, Győr

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Local Institution - 0585, Zagreb

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National Taiwan University Hospital, Taipei

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Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Orbassano

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Local Institution - 0563, Bangkok

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Local Institution - 0618, White Plains

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Local Institution - 0602, Riyadh

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Local Institution - 0176, Mexico City

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Vivantes Klinikum Neukölln, Berlin

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Local Institution - 0562, Riyadh

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Evangelische Lungenklinik Berlin, Berlin

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Local Institution - 0636, Marseille

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Assistance Publique Hôpitaux de Marseille - Hôpital Nord, Marseille

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Centre François Baclesse, Caen

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CHUAC-Hospital Teresa Herrera, A Coruña

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CHUS - Hospital Clinico Universitario, Santiago de Compostela

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Ospedale San Martino, Genova

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Local Institution - 0657, York

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Local Institution - 0619, Dubrovnik

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Local Institution - 0639, Split

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Local Institution - 0385, Columbia

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Centre Georges François Leclerc, Dijon

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Local Institution - 0556, Varese

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Gachon University Gil Medical Center, Namdong-gu

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Local Institution - 0614, Jeddah

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Malteser Krankenhaus St. Franziskus-Hospital, Flensburg

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Local Institution - 0583, Saltillo

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Pius Hospital Oldenburg, Oldenburg

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Fondazione IRCCS Policlinico San Matteo, Pavia

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Hospital General Universitario Gregorio Marañon, Madrid

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Hospital Universitario Ramón y Cajal, Madrid

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Hospital Clinico San Carlos, Madrid

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Hospital Universitario 12 de Octubre, Madrid

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Local Institution - 0672, Salisbury

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Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda

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Chungbuk National University Hospital, Cheongju-si

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Local Institution - 0624, Asheville

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H.R.U Málaga - Hospital General, Málaga

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CHRU de Brest, Brest

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Local Institution - 0658, Greenville

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Local Institution - 0031, Marietta

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Praxis Onkologie am Raschplatz, Hanover

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Local Institution - 0392, Fort Eisenhower

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Local Institution - 0567, Osijek

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Local Institution - 0175, Chihuahua City

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Local Institution - 0651, Gainesville

NOT_YET_RECRUITING

Local Institution - 0621, Palm Bay

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Local Institution - 0377, Tamarac

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Local Institution - 0647, Tampa

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Local Institution - 0550, Istanbul

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Local Institution - 0548, Stanbul

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Institut Régional du Cancer Montpellier, Montpellier

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Local Institution - 0549, Istanbul

NOT_YET_RECRUITING

Local Institution - 0200, Izmir

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Local Institution - 0073, Padua

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UKGM Gießen/Marburg, Giessen

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Local Institution - 0669, Pontevedra

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Chu Grenoble Alpes, La Tronche

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Local Institution - 0565, Muang

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Local Institution - 0566, Louisville

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Hospital Universitario Virgen Del Rocio, Seville

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Local Institution - 0366, Edgewood

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University General Hospital of Larissa, Larissa

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Local Institution - 0579, Pachuca

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Azienda Ospedaliero Universitaria di Parma, Parma

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Local Institution - 0620, Columbus

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Local Institution - 0178, Guadalajara

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Evangelisches Krankenhaus Herne - Eickel, Herne

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Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes, Saint-Herblain

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Hospital Arnau de Vilanova, Valencia

WITHDRAWN

Local Institution - 0495, Valencia

NOT_YET_RECRUITING

Local Institution - 0423, Munster

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"IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) Dino Amadori", Meldola

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Pusan National University Hospital, Busan

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Local Institution - 0560, Angers

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Azienda Ospedaliera Universitaria Careggi, Florence

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Pusan National University Yangsan Hospital, Yangsan

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Local Institution - 0664, Rijeka

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Klinikum Köln-Merheim, Cologne

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Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois, Vandœuvre-lès-Nancy

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Local Institution - 0528, Hemer

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Local Institution - 0665, Arlington Heights

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Centrum für Hämatologie und Onkologie Bethanien, Frankfurt am Main

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Chu Gabriel Montpied, Clermont-Ferrand

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Local Institution - 0591, Monterrey

WITHDRAWN

Local Institution - 0159, Mulhouse

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Instituto Tumori Giovanni Paolo II, Bari

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Local Institution - 0517, Stuttgart

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Yitzhak Shamir Medical Center, Ẕerifin

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Local Institution - 0644, Shreveport

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Local Institution - 0181, Puebla City

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Local Institution - 0638, Puebla City

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Chi Mei Hospital - Liouying Branch, Tainan City

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Klinikum Esslingen, Esslingen am Neckar

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Local Institution - 0133, Paris

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Hopitaux Universitaires Paris Centre-Hopital Cochin, Paris

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Local Institution - 0652, Laredo

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Local Institution - 0622, San Antonio

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CHU d'Amiens-Picardie - Hôpital Sud, Amiens

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A.O.R.N. Ospedale dei Colli - Monaldi V., Naples

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Local Institution - 0442, Denver

WITHDRAWN

Local Institution - 0191, Puerto Colombia

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Klinikum der Ludwig-Maximilians-Universitaet Muenchen, München

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Centrum Onkologii im. Prof. Franciszka Lukaszczyka, Bydgoszcz

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Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren, Limoges

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Local Institution - 0670, Ulm

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Local Institution - 0564, Hat Yai

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Local Institution - 0202, Long Beach

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Local Institution - 0180, Veracruz

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Hôpital Ambroise Paré, Boulogne-Billancourt

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Local Institution - 0643, Newport Beach

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Local Institution - 0581, Fullerton

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Local Institution - 0666, Orange

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Local Institution - 0623, Santa Barbara

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Gustave Roussy, Villejuif

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Universitaetsklinikum Wuerzburg, Würzburg

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Beijing Cancer hospital, Beijing

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Spitalul Municipal Schuller Ploiești, Ploieşti

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Beijing Peking Union Medical College Hospital, Beijing

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Beijing Chest Hospital,Capital Medical University, Beijing

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The First Hospital of China Medical University, Shenyang

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Shengjing Hospital of China Medical University, Shenyang

NOT_YET_RECRUITING

Local Institution - 0312, New Delhi

NOT_YET_RECRUITING

Local Institution - 0511, New Delhi

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Liaoning Cancer Hospital, Shenyang

NOT_YET_RECRUITING

Local Institution - 0135, New Delhi

WITHDRAWN

Local Institution - 0189, Bogotá

NOT_YET_RECRUITING

Local Institution - 0671, Bogota

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The First Hospital of Jilin University, Changchun

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Harbin Medical University Cancer Hospital, Harbin

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Local Institution - 0253, Valledupar

NOT_YET_RECRUITING

Local Institution - 0470, Shanghai

WITHDRAWN

Local Institution - 0381, Shanghai

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Shanghai East Hospital, Shanghai

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"Centrul de Oncologie Sfântul Nectarie", Craiova

NOT_YET_RECRUITING

Local Institution - 0371, Nanjing

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The First Affiliated Hospital of Soochow University, Suzhou

NOT_YET_RECRUITING

Local Institution - 0153, Varanasi

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Northern Jiangsu People's Hospital, Yangzhou

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Anhui Provincial Hospital, Hefei

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Local Institution - 0167, Montería

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The First Afflilated Hospital of Bengbu Medical College, Bengbu

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Shandong Cancer Hospital, Jinan

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LinYi Cancer Hospital, Linyi

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Tianjin Medical University General Hospital, Tianjin

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Cabinet Medical Oncomed, Timișoara

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The first Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou

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Zhejiang Cancer Hospital, Hangzhou

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Taizhou Hospital of Zhejiang Province, Taizhou

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The Second Affiliated Hospital of Nanchang University, Nanchang

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Fujian Medical University Union Hospital, Fuzhou Fujian

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The First Affiliated hospital of Xiamen University, Xiamen

NOT_YET_RECRUITING

Local Institution - 0136, Ahmedabad

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Local Institution - 0230, Ahmedabad

NOT_YET_RECRUITING

Local Institution - 0154, Mumbai

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Cardiomed SRL Cluj-Napoca, Cluj-Napoca

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Institutul Oncologic Cluj, Cluj-Napoca

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Institutul Oncologic Cluj, Cluj-Napoca

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Chongqing University Cancer Hospital, Chongqing

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SC Radiotherapy Center Cluj SRL, Florești

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Hunan Cancer Hospital, Changsha

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Tongji Hospital Tongji Medical,Science & Technology, Wuhan

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The First Affiliated Hospital of Xinxiang Medical University, Xinxiang

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Nanyang City Center Hospital, Nanyang

NOT_YET_RECRUITING

Local Institution - 0661, Hyderabad

NOT_YET_RECRUITING

Local Institution - 0663, Hyderabad

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The First Affiliated Hospital of Guangzhou Medical University, Guangzhou

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Cancer Hospital of Shantou University Medical College, Shantou

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ShenZhen People's Hospital, Shenzhen

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Guangxi Medical University Affiliated Tumor Hospital, Nanning

NOT_YET_RECRUITING

Local Institution - 0222, Visakhapatnam

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Sichuan Cancer hospital, Chengdu

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West China Hospital, Sichuan University, Chengdu

NOT_YET_RECRUITING

Local Institution - 0224, Madurai

NOT_YET_RECRUITING

Local Institution - 0170, Floridablanca

NOT_YET_RECRUITING

Local Institution - 0155, Thiruvananthapuram

NOT_YET_RECRUITING

Local Institution - 0221, Kolkata

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S.C. Centrul de Oncologie Euroclinic S.R.L., Iași

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Institutul Regional de Oncologie, Iași

NOT_YET_RECRUITING

Local Institution - 0161, Howrah

NOT_YET_RECRUITING

Local Institution - 0226, Bhubaneswar

NOT_YET_RECRUITING

Local Institution - 0173, Santiago de Cali

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Affidea Constanța, Constanța

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Ovidius Clinical Hospital OCH, Ovidiu

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Carmel Hospital, Haifa

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Rabin Medical Center, Petah Tikva

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Sheba Medical Center, Ramat Gan

NOT_YET_RECRUITING

Local Institution - 0307, Akashi

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FALP, Santiago

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Bradfordhill, Recoleta

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Hadassah Medical Center, Jerusalem

NOT_YET_RECRUITING

Local Institution - 0301, Sendai

NOT_YET_RECRUITING

Local Institution - 0240, Barretos

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CEDOES, Vitória

NOT_YET_RECRUITING

Local Institution - 0347, Birmingham

NOT_YET_RECRUITING

Local Institution - 0019, Boston

NOT_YET_RECRUITING

Local Institution - 0437, Worcester

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Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires

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IDIM - Instituto de Investigaciones Metabólicas, Ciudad de Buenos Aires

RECRUITING

Hospital Italiano de Buenos Aires, ABB

NOT_YET_RECRUITING

Local Institution - 0571, Buenos Aires

RECRUITING

Clinica Adventista Belgrano, CABA

NOT_YET_RECRUITING

Local Institution - 0257, Salvador

NOT_YET_RECRUITING

Local Institution - 0244, Belo Horizonte

NOT_YET_RECRUITING

Local Institution - 0235, Ijuí

NOT_YET_RECRUITING

Local Institution - 0233, Porto Alegre

NOT_YET_RECRUITING

Local Institution - 0238, Santa Cruz do Sul

RECRUITING

Hospital de Amor Amazônia, Porto Velho

NOT_YET_RECRUITING

Local Institution - 0237, Blumenau

NOT_YET_RECRUITING

Local Institution - 0245, Itajaí

RECRUITING

Advanze Pesquisa, São Carlos

NOT_YET_RECRUITING

Local Institution - 0239, São José do Rio Preto

NOT_YET_RECRUITING

Local Institution - 0254, São Paulo

NOT_YET_RECRUITING

Local Institution - 0236, Rio de Janeiro

NOT_YET_RECRUITING

Local Institution - 0258, São Paulo

NOT_YET_RECRUITING

Local Institution - 0074, Halifax

NOT_YET_RECRUITING

Local Institution - 0559, Montreal

RECRUITING

Fourth Hospital of Hebei Medical University, Shijiazhuang

RECRUITING

Shanxi Cancer Hospital, Taiyuan

NOT_YET_RECRUITING

Local Institution - 0580, Medellín

NOT_YET_RECRUITING

Local Institution - 0171, Rionegro

RECRUITING

Universitätsklinikum Halle, Halle

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SRH Wald-Klinikum Gera GmbH, Gera

RECRUITING

Universitätsklinikum Jena, Jena

NOT_YET_RECRUITING

Local Institution - 0675, Halle

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Errikos Dunant Hospital Center, Athens

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"Thoracic General Hospital of Athens I Sotiria", Athens

RECRUITING

Cork University Hospital, Cork

RECRUITING

Mater Private Hospital - Dublin, Dublin

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St. James's Hospital, Dublin

NOT_YET_RECRUITING

Local Institution - 0100, Dublin

RECRUITING

Beaumont Hospital, Dublin, Dublin

RECRUITING

Istituto Nazionale Tumori Regina Elena, Rome

NOT_YET_RECRUITING

Local Institution - 0607, Nagoya

NOT_YET_RECRUITING

Local Institution - 0305, Nagoya

NOT_YET_RECRUITING

Local Institution - 0298, Sapporo

NOT_YET_RECRUITING

Local Institution - 0304, Kanazawa

NOT_YET_RECRUITING

Local Institution - 0302, Sagamihara

NOT_YET_RECRUITING

Local Institution - 0369, Yokohama

NOT_YET_RECRUITING

Local Institution - 0306, Kashihara

NOT_YET_RECRUITING

Local Institution - 0368, Kurashiki

NOT_YET_RECRUITING

Local Institution - 0642, Hirakata

NOT_YET_RECRUITING

Local Institution - 0303, Hidaka

NOT_YET_RECRUITING

Local Institution - 0300, Ina-machi

NOT_YET_RECRUITING

Local Institution - 0606, Hamamatsu

NOT_YET_RECRUITING

Local Institution - 0299, Shimotsuga

NOT_YET_RECRUITING

Local Institution - 0674, Bunkyo Ku

NOT_YET_RECRUITING

Local Institution - 0343, Toyoma

NOT_YET_RECRUITING

Local Institution - 0542, Iwakuni

NOT_YET_RECRUITING

Local Institution - 0346, Aomori

NOT_YET_RECRUITING

Local Institution - 0310, Fukuoka

NOT_YET_RECRUITING

Local Institution - 0367, Fukushima

NOT_YET_RECRUITING

Local Institution - 0308, Kumamoto

NOT_YET_RECRUITING

Local Institution - 0297, Osaka

NOT_YET_RECRUITING

Local Institution - 0309, Osaka

NOT_YET_RECRUITING

Local Institution - 0615, Maastricht

RECRUITING

Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL), Amsterdam

RECRUITING

Med-Polonia Sp. z o. o., Poznan

RECRUITING

Szpital Specjalistyczny im. Henryka Klimontowicza, Gorlice

RECRUITING

Pratia MCM Krakow, Krakow

NOT_YET_RECRUITING

Local Institution - 0205, Wroclaw

RECRUITING

Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie, Lublin

RECRUITING

Pratia Onkologia Katowice, Katowice

RECRUITING

Szpital Specjalistyczny w Prabutach Spolka z o.o., Prabuty

RECRUITING

Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon

RECRUITING

Instituto Portugês de Oncologia de Coimbra Francisco Gentil, Coimbra

RECRUITING

Centro Hospitalar do Porto - Hospital de Santo António, Porto

RECRUITING

SC Memorial Healthcare International SRL, Bucharest

RECRUITING

Institutul Oncologic Bucuresti, Bucharest

RECRUITING

Severance Hospital, Yonsei University Health System, Seoul

RECRUITING

Konkuk University Medical Center, Seoul

RECRUITING

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul

RECRUITING

Korea University Guro Hospital, Seoul

RECRUITING

Hospital Universitari Vall d'Hebron, Barcelona

WITHDRAWN

Local Institution - 0497, Hospitalet

WITHDRAWN

Local Institution - 0505, Barcelona

RECRUITING

Hospital Son Llàtzer, Palma

NOT_YET_RECRUITING

Local Institution - 0199, Izmir, Karsiyaka

NOT_YET_RECRUITING

Local Institution - 0197, Adana

NOT_YET_RECRUITING

Local Institution - 0201, Ankara

NOT_YET_RECRUITING

Local Institution - 0194, Ankara

NOT_YET_RECRUITING

Local Institution - 0198, Ankara

RECRUITING

University College London Hospital, London

RECRUITING

Guy's & St Thomas' NHS Foundation Trust, London

RECRUITING

Heartlands Hospital, Birmingham

WITHDRAWN

Local Institution - 0545, Guildford

RECRUITING

The Royal Surrey County Hospital, Guildford

WITHDRAWN

Local Institution - 0093, Manchester